Protein Alignment Shaw and kcng1

DIOPT Version :10

• Sequence 1: NP_001137782.1
• Gene: Shaw / 33599
• FlyBaseID: FBgn0003386
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001096675.1
• Gene: kcng1 / 100125206
• XenbaseID: XB-GENE-1011042
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 452
• Identity: 140/452 - (30%)
• Similarity: 224/452 - (49%)
• Gaps: 59/452 - (13%)

  Fly    22 DSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPIL----------NEYFFDRHPGV 76
            |.::..::||||.|:.....||::.|.|||.:| :..:|:|.||          ||:||||:||.
 Frog    59 DRKHHAIINVGGFRYLLPWTTLEEFPLTRLGQL-KLCSNFDEILSICDDYDVTCNEFFFDRNPGA 122

  Fly    77 FAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLD 141
            |..:|.:.:.|||....::|...|:|||.:||::.:.:|.||...|.|..:....|.:.:...::
 Frog   123 FRTILTFLQVGKLRLLREMCALSFQEELLYWGIEEDNLEWCCKRRYIQKMEEFAELNLREEELIE 187

  Fly   142 TEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSF 206
            .|..||.|...|...              ....:..:.::|.|....|....:||.|:.|:.::.
 Frog   188 NENASEPEDESKLDI--------------CMRHLGDMVEKPQSGLPGKIFACLSVLFVTITAVNL 238

  Fly   207 CLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNK 271
            .:.|.||:|....:.:..|....                .|.:|.||..||:.|.|:|||.:|:|
 Frog   239 SISTMPDLREEEEKGVCSKMCYN----------------IFIVESVCVGWFSLEFLLRFIQAPSK 287

  Fly   272 WEFIKSSVNIIDYIATLSFYIDLVLQRFA----------SHLENAD-ILEFFSIIRIMRLFKLTR 325
            :.||:..:|:||.:|.|.:||.||:...:          |:|:... :|.....:||:.:.:|.|
 Frog   288 FAFIRRPLNLIDIVAILPYYITLVVDNTSDGQKKPGSGNSYLDKVGLVLRILRALRILYVMRLAR 352

  Fly   326 HSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTM 390
            ||.||:.|..|.|...:|..||:.||.:.|.:||.|:|..|. :.....:|.|||...|||::||
 Frog   353 HSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYLIEN-EMADSQEFTSIPACYWWAVITM 416

  Fly   391 TTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVL 452
            ||||||||.|::..|..|.....|:|:|.:|.||..|...|:..|      .:|.:::.|::
 Frog   417 TTVGYGDMVPRSIPGQVVALSSILSGILLMAFPVTSIFHTFSRSY------IELKQEQERLM 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shaw	NP_001137782.1	BTB_Shaw-like	24..135	CDD:349723	42/120 (35%)
		Ion_trans	188..439	CDD:459842	88/261 (34%)
		PRK14959	<418..>585	CDD:184923	9/35 (26%)
kcng1	NP_001096675.1	BTB_POZ_KCNG1_2	59..172	CDD:349728	42/113 (37%)
		Ion_trans	221..461	CDD:459842	87/256 (34%)