DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Arhgap17

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_038945137.1	Gene:	Arhgap17 / 63994	RGDID:	628767	Length:	866	Species:	Rattus norvegicus

Alignment Length:	470	Identity:	107/470 - (22%)
Similarity:	179/470 - (38%)	Gaps:	113/470 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 AEAIVQLVRTLNKTVRVRTKSRPKRKPDIRDVFREFDEQGTVTRSR------SATPDSLD--SLQ 138
            :|.::|:.|.|: |||.......||   :...|:  .:.||....|      :|...::.  |.|
  Rat    26 SEDLLQIERRLD-TVRSMCHHSHKR---LIACFQ--GQHGTDAERRHKKLPLTALAQNMQEASAQ 84

  Fly   139 IDEAWTNNSLPTFVNVYEKNTETAIQCVEQSNEI--YLKQNLRRTPSAPPKSGTYADIFRGSQVR 201
            ::|:.....|.|              |.:..|::  .|.|:               ::|...::.
  Rat    85 LEESLLGKMLET--------------CGDAENQLAFELSQH---------------EVFVEKEIM 120

  Fly   202 CDIPLYSADGVELLGYSRIGTIQFPRN---RSVSDPFCSIGRSKESRSENDARSQKKKSS-EVLS 262
              .|||....||      |..||..|.   |.|.|......|..::...:....|...|. :.|.
  Rat   121 --DPLYGIAEVE------IPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLK 177

  Fly   263 ASENECGRLLPMPYNVLSFESICRDSSSLDSCEVLDTCDIPSTLFTDVVLISETDMKRLQTILWL 327
            ...:|.|..:..          |:|..:.|...               .:..|.:..:....| |
  Rat   178 EEMDEAGNKVEQ----------CKDQLAADMYN---------------FMAKEGEYGKFFVTL-L 216

  Fly   328 ELATIFDRNKVS-LDKRKPFKRRRKE---EGNLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIG 388
            |....:.|..:: |:|..|..|..::   |...||..:...::|    :|.:   :.|.:|..:.
  Rat   217 EAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKR----SGRE---IALPIEACVM 274

  Fly   389 ELLRRGSREEGLLRIGGHKQKTELLYNELEST------FYQNPDNLDNLFRTATVHELSSLLKRW 447
            .||..|.:||||.|||....|.:.|...|:.:      ||.:|            |.::..||.:
  Rat   275 LLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDP------------HAVAGALKSY 327

  Fly   448 LRELPQPLLTNELIQLFYQCHTLPSID-QMNALSILCHLLPPENRNTLRSLLSFFNIIINLKDIN 511
            |||||:||:|..|.:.:.|..::...| ::..|...|..|||:|....|.|:.|...:....|:|
  Rat   328 LRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVN 392

  Fly   512 KMNVHNVATIMAPSM 526
            ||...|:|.::.|::
  Rat   393 KMTPSNIAIVLGPNL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	52/178 (29%)
Arhgap17	XP_038945137.1	BAR_Rich1	13..257	CDD:153302	57/299 (19%)
Arhgap17	XP_038945137.1	RhoGAP_nadrin	246..446	CDD:239851	53/181 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910