DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment conu and Arhgap33

DIOPT Version :9

Sequence 1:	NP_001036454.1	Gene:	conu / 3355133	FlyBaseID:	FBgn0039994	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_038949821.1	Gene:	Arhgap33 / 100362311	RGDID:	2318374	Length:	1354	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	67/311 - (21%)
Similarity:	118/311 - (37%)	Gaps:	64/311 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 KRKPFKRRRKEEG----NLFGVSINALIRRDQQVTGTDSSLVPLFLEKLIGELLRRGSREEGLLR 402
            :.:|.::|.::.|    .:||..:...:..    :|.|   ||..| :...|.:......:|:.|
  Rat   363 RSRPSRQRLRQRGILRQRVFGCDLGEHLSN----SGQD---VPQVL-RCCSEFIEAHGVVDGIYR 419

  Fly   403 IGGHKQKTELLYNELESTFYQNPDNLDNLFRTA---TVHELSSLLKRWLRELPQPLLTNELIQLF 464
            :.|.....:.|.:|.:|      :.:..|...|   .:|.:|||.|.:.||||.||||.:|...|
  Rat   420 LSGVSSNIQRLRHEFDS------ERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKF 478

  Fly   465 YQCHTLPSIDQ-MNALSILCHLLPPENRNTLRSLLSFFNIIINLKDINKMNVHNVATIMAPSMFP 528
            .:..::|..:: :..:..:...|||.:..||..||.....:........|:..|:|.:.||::..
  Rat   479 SEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLR 543

  Fly   529 PRYIHPSDNNSIA--EQVRMAAQCCR--LTNILIL------------RGEKLFQVPNNL------ 571
            ...:........|  .:||:.:....  ||::.:|            .|..|...|.:|
  Rat   544 SMELESVGLGGAAAFREVRVQSVVVEFLLTHVEVLFSDTFTSAGLDPAGRCLLPRPKSLAGSSPS 608

  Fly   572 -----IVESQKTMMGKKGW---------------HRHRNSNEITAKPSGKA 602
                 :.|:|....|:.|.               .|.|...|...||.|.:
  Rat   609 TRLLTLEEAQARTQGRLGTPTEPTTPKTPASPVERRKRERVEKQRKPGGSS 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conu	NP_001036454.1	RhoGAP_ARHGAP18	356..576	CDD:239856	55/250 (22%)
Arhgap33	XP_038949821.1	PX_TCGAP	125..237	CDD:132832
		SH3_ARHGAP32_33	259..312	CDD:212769
		RhoGAP_CdGAP	380..574	CDD:239849	48/207 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910