Protein Alignment rl and KSS1

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_011554.3
• Gene: KSS1 / 852931
• SGDID: S000003272
• Length: 368
• Species: Saccharomyces cerevisiae
• Alignment Length: 365
• Identity: 180/365 - (49%)
• Similarity: 237/365 - (64%)
• Gaps: 30/365 - (8%)

  Fly    32 FEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTLREITILTRF-KHEN 95
            |::..:|..:..|||||||.|.||....:..:||||||.||..:.:..||:|||.:|..| :|||
Yeast     7 FDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHEN 71

  Fly    96 IIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQR-----LSNDHICYFLYQILRGLKYIHS 155
            ||.|.|.:|..|||::..||:|:.||||||.|::..|.     ||:||:.||.|||||.||.|||
Yeast    72 IISILDKVRPVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHS 136

  Fly   156 ANVLHRDLKPSNLLLNKTCDLKICDFGLARI----ADPEHDHTGFLTEYVATRWYRAPEIMLNSK 216
            |.|:|||:||||||||..||||:|||||||.    :|......||:||||||||||||||||..:
Yeast   137 AQVIHRDIKPSNLLLNSNCDLKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQ 201

  Fly   217 GYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLP 281
            .||.::||||.|||||||:|.:|:|||:.|..||..||.|||:||.:|...|.:::|:.|:.:||
Yeast   202 EYTTAMDIWSCGCILAEMVSGKPLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLP 266

  Fly   282 FKPNVPWAKLFPNADAL--ALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRI 344
            .:|.:||..::...|..  .:|||.|||.|||.|||...|||.||||..|:||.|||  |.| .:
Yeast   267 MRPPLPWETVWSKTDLNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMYHDPSDEP--EYP-PL 328

  Fly   345 NM---------------ENDDISRDALKSLIFEETLKFKE 369
            |:               |.:::..:.||.::::|.:|..|
Yeast   329 NLDDEFWKLDNKIMRPEEEEEVPIEMLKDMLYDELMKTME 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	178/360 (49%)
KSS1	NP_011554.3	Protein Kinases, catalytic domain	7..365	CDD:473864	178/360 (49%)