Protein Alignment rl and CDK16

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_011542222.1
• Gene: CDK16 / 5127
• HGNCID: 8749
• Length: 571
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 127/363 - (34%)
• Similarity: 186/363 - (51%)
• Gaps: 45/363 - (12%)

  Fly    28 RGQIFEVG----PRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRT-LREITI 87
            |..:.|:|    ..||||..:|||.|..|......||:..||:|:|. .||:.....| :||:::
Human   225 RVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIR-LEHEEGAPCTAIREVSL 288

  Fly    88 LTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLL-KTQRLSNDH-ICYFLYQILRGL 150
            |...||.||:.:.||:..:     :.:.:|...::.||.:.| ....:.|.| :..||:|:||||
Human   289 LKDLKHANIVTLHDIIHTE-----KSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGL 348

  Fly   151 KYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIAD-PEHDHTGFLTEYVATRWYRAPEIMLN 214
            .|.|...||||||||.|||:|:..:||:.||||||... |    |...:..|.|.|||.|:|:|.
Human   349 AYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIP----TKTYSNEVVTLWYRPPDILLG 409

  Fly   215 SKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECII-NEKARNYLE 278
            |..|:..||:|.||||..||.:.||:|||....:||:.|..:||:|:.:....|: ||:.:.|
Human   410 STDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTY-- 472

  Fly   279 SLPFKPNVPWAKL------FPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPV 337
                  |.|..:.      .|..|:...|||.|:|.|....||..|:|:.||:   :...|:
Human   473 ------NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPF---FLSLGE--- 525

  Fly   338 AEVPFRINMENDDISRDALKSLIFEETLKFK-ERQPDN 374
                 ||:...|..|..|||.:..::....: ...||:
Human   526 -----RIHKLPDTTSIFALKEIQLQKEASLRSSSMPDS 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	124/348 (36%)
CDK16	XP_011542222.1	STKc_PCTAIRE1	236..532	CDD:270854	117/324 (36%)