DRSC/TRiP Functional Genomics Resources

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Protein Alignment rl and nmo

DIOPT Version :10

Sequence 1:NP_001015122.1 Gene:rl / 3354888 FlyBaseID:FBgn0003256 Length:376 Species:Drosophila melanogaster
Sequence 2:XP_315928.3 Gene:nmo / 1276565 VectorBaseID:AGAMI1_011166 Length:442 Species:Anopheles gambiae


Alignment Length:404 Identity:153/404 - (37%)
Similarity:223/404 - (55%) Gaps:58/404 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 SGSVVNGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAY----------IGEGAYGMVVSADDTLTN 61
            |.|:|.| |:...||       |.|......|.:...          ||.||:|:|.:..|....
Mosquito    19 SMSLVQG-GAAGAPQ-------GAILAAAAPYFQPPAVPQDVQPDRPIGYGAFGVVWAVTDPRDG 75

  Fly    62 QRVAIKKI-SPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDL 125
            :|||:||: :.|:.....:|..||:.:|..|||||::...|||:...:|..:::|::..|:::||
Mosquito    76 RRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDL 140

  Fly   126 YKLL-KTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADP 189
            :|:: ..|.||.|||..|||||||||||:|||.:||||:||.|||:|..|.||||||||||:.:|
Mosquito   141 HKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEP 205

  Fly   190 EHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHIL 254
              |.:..:|:.|.|::||||||::.::.|:.::|:||||||..|:|..|.:|..:..:.||..|.
Mosquito   206 --DQSKHMTQEVVTQYYRAPEILMGARHYSAAVDVWSVGCIFGELLGRRILFQAQSPVQQLELIT 268

  Fly   255 GVLGSPSRDDLE--CIINEKARNYLESLPFKPNVPWA--KLFPNADALALDLLGKMLTFNPHKRI 315
            .:||:||.:|:.  |   |.||:::.....||....|  .|..:|...|:.||.:||.|:|.|||
Mosquito   269 ELLGTPSLEDMRHAC---EGARSHMLRRAPKPRSLTALYTLSTHATHEAVHLLCQMLVFDPDKRI 330

  Fly   316 PVEEALAHPYLEQ---------------------YYDPGDEPVAEVPFRINMENDDISRDALKSL 359
            .|.:||||||:::                     .|....||.|...|      ||:....|.|:
Mosquito   331 SVIDALAHPYVDEGRLRYHSCMCKCCYTTSAGMRQYTGEFEPSATQAF------DDLWERKLTSV 389

  Fly   360 --IFEETLKFKERQ 371
              :.||..||...|
Mosquito   390 QQVKEEMHKFIAEQ 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rlNP_001015122.1 STKc_ERK1_2_like 32..366 CDD:270839 141/372 (38%)
nmoXP_315928.3 STKc_NLK 51..423 CDD:173748 143/364 (39%)

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