DRSC/TRiP Functional Genomics Resources

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Protein Alignment rl and Mapk8

DIOPT Version :10

Sequence 1:NP_001015122.1 Gene:rl / 3354888 FlyBaseID:FBgn0003256 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_446281.2 Gene:Mapk8 / 116554 RGDID:621506 Length:427 Species:Rattus norvegicus


Alignment Length:376 Identity:144/376 - (38%)
Similarity:229/376 - (60%) Gaps:34/376 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 NGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQ 75
            |...|.|:..|...|::        ||..|..||.||.|:|.:|.|.:..:.|||||:| ||::|
  Rat     8 NNFYSVEIGDSTFTVLK--------RYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQ 64

  Fly    76 TYCQRTLREITILTRFKHENIIDIRDILRVD-SIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHI 139
            |:.:|..||:.::....|:|||.:.::.... |:::.:|||||..||:.:|.::::.: |.::.:
  Rat    65 THAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQME-LDHERM 128

  Fly   140 CYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGF-LTEYVAT 203
            .|.|||:|.|:|::|||.::||||||||:::...|.|||.||||||.|.     |.| :|.||.|
  Rat   129 SYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAG-----TSFMMTPYVVT 188

  Fly   204 RWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECI 268
            |:|||||::| ..||.:::|:||||||:.||:..:.:|||:.|:||.|.::..||:|..:.:: .
  Rat   189 RYYRAPEVIL-GMGYKENVDLWSVGCIMGEMVCLKILFPGRDYIDQWNKVIEQLGTPCPEFMK-K 251

  Fly   269 INEKARNYLESLPFKPNVPWAKLFPN----AD--------ALALDLLGKMLTFNPHKRIPVEEAL 321
            :....|.|:|:.|......:.||||:    ||        :.|.|||.|||..:..|||.|:|||
  Rat   252 LQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEAL 316

  Fly   322 AHPYLEQYYDP--GDEPVAEVPFRINMENDDISRDALKSLIFEETLKFKER 370
            .|||:..:|||  .:.|..::|.: .::..:.:.:..|.||::|.:..:||
  Rat   317 QHPYINVWYDPSEAEAPPPKIPDK-QLDEREHTIEEWKELIYKEVMDLEER 366

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rlNP_001015122.1 STKc_ERK1_2_like 32..366 CDD:270839 137/350 (39%)
Mapk8NP_446281.2 STKc_JNK 25..360 CDD:270840 136/343 (40%)
TXY 183..185 1/1 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 368..411
Blue background indicates that the domain is not in the aligned region.

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