Protein Alignment: CG3347 and KDM7A

• Sequence 1: NP_001285579.1
• Gene: CG3347
• FlyBaseID: FBgn0031513
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_085150.1
• Gene: KDM7A
• HGNCID: 22224
• Length: 941
• Species: Homo sapiens
• Alignment Length: 610
• Identity: 124/611 (20%)
• Similarity: 200/611 (33%)
• Gaps: 185/611 (30%)

  Fly    11 GEADTAVSSKDVYCICRQSH-INGFMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTEC------ 68
            |.|........|||:|||.: :|.|||.||.|.:||||.|:|:..:.....|.|:|..|
Human    27 GRASAPPPPPPVYCVCRQPYDVNRFMIECDICKDWFHGSCVGVEEHHAVDIDLYHCPNCAVLHGS 91

  Fly    69 --------FRKNPLLKCTYKKSPSTTGVPKTPKTPKTPKTPKN---------------------- 103
                    :.::...:......|...|.....|..::...|..
Human    92 SLMKKRRNWHRHDYTEIDDGSKPVQAGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGF 156

  Fly   104 ------PKTPKTPKNSKTPKTA-----------RIINSIGVRQNPRRRSTFVQERPSEVPNPSRQ 151
                  ||.........:|..:           ::|:.|.|.:....:.| :........||:|
Human   157 DVPIMVPKLDDLGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSKMT-LHNYVKYFMNPNR- 219

  Fly   152 STKLQKAVNYENATEEPTEDAEKVDQKPKKTAKKKN--------PKP----------EDKVTD-- 196
             .|:...::.|.:..:.:|..| |....||.:..:|        |||          :|..||
Human   220 -PKVLNVISLEFSDTKMSELVE-VPDIAKKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFH 282

  Fly   197 -DAQKPAV-------EKLFE-SKGTQCNM--FRDWSKYVPPENSKKRGTCFTVFCQQLARSCSRY 250
             |....:|       ||:|. .|.|..|:  :..||..|         |...||.......|.:
Human   283 IDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSV---------TQSEVFFGDKVDKCYK- 337

  Fly   251 CCDECGNFTAITNVFALGLLPNMPAMKVAMGHVGLLLGNDLTN-NQKSNKNSEASESKTETKPKV 314
            |..:.|:...:...:...:|.:...|  |.|      ||.|.| |..........|.:.:|....
Human   338 CVVKQGHTLFVPTGWIHAVLTSQDCM--AFG------GNFLHNLNIGMQLRCYEMEKRLKTPDLF 394

  Fly   315 KKPKSEGRKSRYRSPSSSLERSPDVSRTAAKRPKLQEELPSSSSRSSRKLVEESRSETERH---- 375
            |.|..|.                 :....||  .|.|.|         |.:.|...:.:.:
Human   395 KFPFFEA-----------------ICWFVAK--NLLETL---------KELREDGFQPQTYLVQG 431

  Fly   376 -KAKHKTSK---KEKTSSQRAYSLSPIPSPKSYRAARNTSETAPNSPVNLKKTFKQKHVISSPTG 436
             ||.|...|   |::..|:.|:.:                      |.|:    :..|:|..
Human   432 VKALHTALKLWMKKELVSEHAFEI----------------------PDNV----RPGHLIKE--- 467

  Fly   437 KKRVCRSQTISADDPLPSQPKSTEVSPMASAGTSSSNKKPVPETSCQKYRKLS----FTDENCEK 497
                 .|:.|.|.:....:|..::..|:....:.|||:...|..|.:|.|||.    .|..|.:.
Human   468 -----LSKVIRAIEEENGKPVKSQGIPIVCPVSRSSNEATSPYHSRRKMRKLRDHNVRTPSNLDI 527

  Fly   498 IKI-IRCIVS--NMSPTEKALLARK 519
            ::: .|.::.  .|.|.|:.:|:.|
Human   528 LELHTREVLKRLEMCPWEEDILSSK 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3347	NP_001285579.1	PHD_SF	23..68	CDD:304600	21/46 (46%)
KDM7A	NP_085150.1	PHD_KDM7	39..88	CDD:277110	22/49 (45%)
		Linker	97..114		0/17 (0%)
		JmjC	234..297	CDD:214721	14/64 (22%)
		cupin_like	269..369	CDD:304367	26/118 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG1632
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900