Protein Alignment CG3347 and cxxc1

DIOPT Version :10

• Sequence 1: NP_722887.2
• Gene: CG3347 / 33538
• FlyBaseID: FBgn0031513
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_031747257.1
• Gene: cxxc1 / 613066
• XenbaseID: XB-GENE-5910691
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 633
• Identity: 136/633 - (21%)
• Similarity: 217/633 - (34%)
• Gaps: 218/633 - (34%)

  Fly    10 FGEAD-TAVSSKD------VYCICRQSHINGFMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTE 67
            |.:|| ||....:      ||||||:..||.|||.||||||||||.||.:...:.:....:||.:
 Frog     5 FSDADLTAAGDTEDGENAPVYCICRKPDINCFMIGCDNCNEWFHGHCINITEKMAKAIREWYCVQ 69

  Fly    68 CFRKNPLLKCTY--KKSPSTTGVPKTPKTPKTPKTPKNPKTPKTPKNSKTP-----KTARI---- 121
            |..|:|.|:..|  |||.......:..:..:|.|..|......:..::|.|     ::||:
 Frog    70 CRDKHPHLEIKYRHKKSKERERETEKDENEETAKNEKKKSGSTSSSSNKVPRQQIKRSARMCGEC 134

  Fly   122 -----------------INSIG----VRQNPRRRSTFVQERPS---------EVP------NPSR 150
                             :...|    :||..|.|...|:.|.|         |.|      .|..
 Frog   135 EACSRTEDCGQCDFCRDMKKFGGPNKIRQKCRLRQCQVRARVSRRAPVSPGAEWPLLSAPVVPGY 199

  Fly   151 QSTKLQKAVNYEN-------ATEEP--------------------------------------TE 170
            ....|||.:..::       .|.||                                      |:
 Frog   200 SILLLQKMLRVKDDDLSLFRDTPEPSSLAGSLSDDDLPLDPELYQELCAGGAFDDHNLPWLSDTD 264

  Fly   171 DAEKVDQKPKKTA-----KKKNPKPEDKVTDDAQKPAVEK---LFESKGTQCNMFRDWSKYVPPE 227
            |...:|...:|.|     .|:..|..||..|:..|...:|   ..::|.::....||:|..
 Frog   265 DTPFLDSVMRKRAVKVKHVKRREKKADKKKDEKYKRHKQKQRHKDKTKHSERTEIRDFSSL---- 325

  Fly   228 NSKKRGTCFTVFCQQLARSCSRYCCDECGNFTAITNVFALGLLPNMPAMKVAMGHVGLLLGNDLT 292
                 ..|....|.|.|||.|:||.|:||                   ||:|...:..:|...:.
 Frog   326 -----RQCLGPSCVQPARSSSKYCSDDCG-------------------MKLAANRIYEILPQRIQ 366

  Fly   293 NNQKSNKNSEASESKTETKPKVKKPKSEGRKSRYRSPSSSLERSPDVSRTAAKRPKLQ------E 351
            ..|:|              |.|  .:.:|:|...|     :.|....:||     |||      .
 Frog   367 QWQQS--------------PCV--AEEQGKKLLER-----IRREQQQART-----KLQNMESRFH 405

  Fly   352 ELPSSSSRSSRKLVEESRSETE---------------RHKAKHKTSKKEKTSSQRAYSLSPIPSP 401
            ||.:..|::.::.:.|.....|               .|....|.:.:.   .:|.|
 Frog   406 ELEALISKAKQQQIREDEETNEGDSDDTDLQIFCVSCGHPINPKVALRH---MERCY-------- 459

  Fly   402 KSYRAARNTSETAPNS--PVNLKKTFKQKHVISSPTGKKRVCRSQTI----SADDPLPSQ----- 455
                 |:..|:|:..|  |..::...:....:.:|..|....|.|.:    |.|..:|:.
 Frog   460 -----AKYESQTSFGSMYPTRIEGATRLFCDVYNPHSKTYCKRLQVLCPEHSRDPKVPADEVCGC 519

  Fly   456 PKSTEVSPMASAGTSSSNKKPVPETSCQK---YRKLSFTDENCEKIKI 500
            |...:|..:      :.:...||:..|.:   :.||...:.:.|::::
 Frog   520 PMVKDVFEL------TGDFCRVPKRKCNRHYCWEKLRRAEVDLERVRL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3347	NP_722887.2	PHD_SF	23..68	CDD:473978	24/44 (55%)
cxxc1	XP_031747257.1	PHD_Cfp1	25..70	CDD:277028	24/44 (55%)
		zf-CXXC	123..170	CDD:366873	7/46 (15%)
		CpG_bind_C	353..589	CDD:463514	44/257 (17%)