DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3347 and E(bx)

DIOPT Version :9

Sequence 1:	NP_001285579.1	Gene:	CG3347 / 33538	FlyBaseID:	FBgn0031513	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001261188.1	Gene:	E(bx) / 44811	FlyBaseID:	FBgn0000541	Length:	2761	Species:	Drosophila melanogaster

Alignment Length:	251	Identity:	57/251 - (22%)
Similarity:	86/251 - (34%)	Gaps:	76/251 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AVSSKDVYCICRQSHING-FMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTECFRKNPLLKCTY 79
            |..::.:||.|||.:... |.||||.|.:||||.|:|:..:..|..|.|.|.||.|||.......
  Fly  2582 ARETQQLYCSCRQPYDESQFYICCDKCQDWFHGRCVGILQSEAEFIDEYVCPECQRKNDANAANM 2646

  Fly    80 KKSPSTTGVPKTPKTPKTPKTPKNPKTPKTPKNSKTPKTARIINSIGVRQNPRRRSTFVQERPSE 144
            ||..|                    ...:..||.             ::|....:|.:
  Fly  2647 KKLTS--------------------NDVEELKNL-------------IKQMQLHKSAW------- 2671

  Fly   145 VPNPSRQSTKLQKAVNYENATEEPTEDAEKVDQKPKKTAKKKNPKPEDKVTDDAQKPAVEKLFES 209
               |..:....::|.:|....:||. |.::::.|                   .:.....||.|.
  Fly  2672 ---PFMEPVDPKEAPDYYKVIKEPM-DLKRMEIK-------------------LESNTYTKLSEF 2713

  Fly   210 KGTQCNMFRDWSKYVPPENSKKRGTCFTVFCQQLARSCSRYCCDECGNFTAITNVF 265
            .|....:|.:...|.|.|:|          ..:.|.:...|...:..||.  .|||
  Fly  2714 IGDMTKIFDNCRYYNPKESS----------FYKCAEALESYFVQKIKNFR--ENVF 2757

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3347	NP_001285579.1	PHD_SF	23..68	CDD:304600	21/45 (47%)
E(bx)	NP_001261188.1	DDT	190..245	CDD:280886
		WHIM1	288..337	CDD:292246
		PHD1_BPTF	341..383	CDD:277034
		BAH	361..>438	CDD:295389
		TNG2	<2423..2638	CDD:227367	24/55 (44%)
		PHD_SF	2533..2579	CDD:304600
		PHD2_3_BPTF	2589..2635	CDD:277035	21/45 (47%)
		Bromo_gcn5_like	2653..2752	CDD:99941	22/151 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1632
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900