Protein Alignment CG3347 and cxxc1a

DIOPT Version :10

• Sequence 1: NP_722887.2
• Gene: CG3347 / 33538
• FlyBaseID: FBgn0031513
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_956893.1
• Gene: cxxc1a / 393571
• ZFINID: ZDB-GENE-040426-1142
• Length: 570
• Species: Danio rerio
• Alignment Length: 620
• Identity: 121/620 - (19%)
• Similarity: 219/620 - (35%)
• Gaps: 191/620 - (30%)

  Fly    22 VYCICRQSHINGFMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTECFRKNPLLKCTYK------ 80
            |||:||:..||.|||.||:|:||||||||.:.....:....:||.:|..|:..|:..|:
Zfish    25 VYCVCRRPDINCFMIGCDSCSEWFHGDCIKISEKTAKTIRVWYCEKCRSKDETLEVKYRPKKSRE 89

  Fly    81 KSPSTTGVPKTPKTPKTPKTPKNPKTPKTPKNSKTPKTARI---------------------INS 124
            |...|.|....|.||......:        :.|:..::||:                     :..
Zfish    90 KEAETDGPDTQPDTPDFKSDGR--------RGSRIKRSARMCGECEACLRTEDCGLCDFCKDMKK 146

  Fly   125 IG----VRQNPRRRSTFVQERPSEVPNPSRQSTKLQKAVNYENA--TEEPTEDAEKVDQK----- 178
            .|    :||..|.|...|:.|  ::.....:...:.|:.:|::.  :||.:|:..::.|:
Zfish   147 FGGPNKIRQKCRLRQCEVRAR--KMLRVKEEEYSMSKSRDYQDGPLSEEYSENELELYQQYCAGQ 209

  Fly   179 ----------------------PKKTAKKKNPKPEDKVTDDAQKPAVEKLFESKGTQCNMFRDWS 221
                                  .||..|.|:.|..:|.::.::|    |..|:|.         .
Zfish   210 YGDNGTGWNSDDDDGSYGESSLRKKAVKVKHVKRREKRSEKSEK----KKEENKS---------R 261

  Fly   222 KYVPPENSKKR---------------GTCFTVFCQQLARSCSRYCCDECGNFTAITNVFALGLLP 271
            |:.|.:..:.|               ..|....|.:.||:.|:||.|:||
Zfish   262 KHKPKQKHRDRVRHSERAEVRDSGGARQCLGPGCVEAARANSKYCSDDCG--------------- 311

  Fly   272 NMPAMKVAMGHVGLLLGNDLTNNQKSNKNSEASESKTETKPKVKKPKSEGRKSRYRSPSSSLERS 336
                ||:|...:..:|...:...|:|...:|                .:|:|...|     :.|.
Zfish   312 ----MKLAANRICEILPQRIQQWQQSPCIAE----------------EQGKKFLER-----IRRE 351

  Fly   337 PDVSR-TAAKRPKLQEELPSSSSRSSRKLVE------ESRSETE--------RHKAKHKTSKKEK 386
            ..::| ...:..|...||....:::.:::|:      |...:|:        .|....|.:.:.
Zfish   352 QQLARMRLTEMEKRFHELEGIIAKAKQQVVQYDEEVNEGDDDTDLQIFCVSCSHSVNPKVALRH- 415

  Fly   387 TSSQRAYSLSPIPSPKSYRAARNTSETAPNS--PVNLKKTFKQKHVISSPTGKKRVCRSQTI--- 446
              .:|.|             |:..|:|:..|  |..::...:....:.:|..|....|.|.:
Zfish   416 --MERCY-------------AKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPE 465

  Fly   447 -SADDPLPSQ-----PKSTEVSPMASAGTSSSNKKPVPETSCQK---YRKLSFTDENCEKIKIIR 502
             |.|..:|:.     |...:|..........|.:|      |.|   :.||...:.:.|::::..
Zfish   466 HSRDPKIPADEVCGCPLVRDVFEPTGEYCRVSKRK------CNKHYCWEKLRRAEVDLERVRVWY 524

  Fly   503 CI--VSNMSPTEKALLARKRMMMKLASEQHIRQAP 535
            .:  :.......|..:..:..:|.|...|.|:..|
Zfish   525 KLDELFEQERNVKTAMTNRAGLMALMPHQTIQHDP 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3347	NP_722887.2	PHD_SF	23..68	CDD:473978	22/44 (50%)
cxxc1a	NP_956893.1	PHD_SF	26..71	CDD:473978	22/44 (50%)
		zf-CXXC	115..162	CDD:366873	7/46 (15%)
		CpG_bind_C	315..550	CDD:463514	43/277 (16%)