DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3347 and Cfp1

DIOPT Version :9

Sequence 1:	NP_001285579.1	Gene:	CG3347 / 33538	FlyBaseID:	FBgn0031513	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_572556.1	Gene:	Cfp1 / 31880	FlyBaseID:	FBgn0030121	Length:	663	Species:	Drosophila melanogaster

Alignment Length:	554	Identity:	122/554 - (22%)
Similarity:	195/554 - (35%)	Gaps:	121/554 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 TAVSSKD-VYCICRQSHINGFMICCDNCNEWFHGDCIGLPANIGEQHDTYYCTECFRKNPLLKCT 78
            |.:..:| .|||||.|..:.|||.||.|.||:||||||:.....:....|||..|.::||.|:..
  Fly    53 TILKQEDQAYCICRSSDCSRFMIGCDGCEEWYHGDCIGITEKEAKHIKQYYCRRCKKENPELQTI 117

  Fly    79 YKKSPSTTGVPKTPKTPKTPKTPKNPKTPKTPKNSKTPKTARIINSIGVRQNPRRRSTFVQERPS 143
            ::       :..|.:...:.....:...|....:...|..|.:.::...:|.|...:...:.:
  Fly   118 FR-------LVATERAAASNAASTSLNAPGVGPSGAAPAAAPVASATTSQQAPPPTTAAAKRK-- 173

  Fly   144 EVPNPSRQSTKLQKAVNYENATEEPT---EDA--EKVDQKPKKTAKKKNPKPEDKVTDDAQKPAV 203
               |.|.:..|:.|..........|.   .||  .:|..||:...:          |...|...|
  Fly   174 ---NSSAREPKMGKRCGTCEGCRRPNCNQCDACRVRVGHKPRCIFR----------TCVVQAATV 225

  Fly   204 EKLFESKGTQCNMFRDWSKYVP-------------PE---NSKKRG--TCFTVFCQQLARSCSRY 250
            .|  ||:.||....|...|..|             ||   |.:.:|  .|:...|...||..|:|
  Fly   226 LK--ESQATQAGPSRKREKAAPKSRNVQVGPRAASPEIFLNPELQGIRQCYGPNCCSHARPQSKY 288

  Fly   251 CCDECGNFTAITNVFALGLLPNMPAMKVAMGHVGLLLGNDLTNNQKSNKNSEASESKTETKPKVK 315
            |.|:||...|...:|.  :||                      .:....|...|.:..||:..:.
  Fly   289 CSDKCGFNLATKRIFQ--VLP----------------------QRLQEWNLTPSRAAEETRKHLD 329

  Fly   316 KPKSEGRKSRYRSPSSSLERSPDVSRTAAKRPKLQEELPSSSSRSSRKLVEESRSE--TERHKAK 378
            ..:.  ::|..|...:.||:..:......:|.| :..:.:..|:.:..:.:|....  |..|:..
  Fly   330 NIRH--KQSLVRFALAELEKRSEELNMVVERAK-RSSIDTLGSQDTADMEDEQSMYCITCGHEIH 391

  Fly   379 HKTSKKEKTSSQRAYSLSPIPSPKSYRAARNTSETAPNSPVNLKKTFKQKHVISSPTGKKR---V 440
            .:|:.|........|.     |..|:.:...|.....|       .|...:..:|.|..||   :
  Fly   392 SRTAIKHMEKCFNKYE-----SQASFGSIFKTRMEGNN-------MFCDFYNPASKTYCKRLRVL 444

  Fly   441 CRSQTISADDPLPSQPKSTEVSPMASAGTSSSNK--KPVPETSCQKYRKLSFTDENCEKIKIIRC 503
            |           |...|..:|:.....|:...|.  .|..| .|:..:|..|.....|||:  |.
  Fly   445 C-----------PEHSKDPKVNDTDVCGSPLVNNVFNPTGE-FCRAPKKNCFKHYAWEKIR--RA 495

  Fly   504 IVSNMSPTEKALLARKRMMMK----LASEQHIRQ 533
            .:.         |.|.|..:|    :..|:.:||
  Fly   496 EID---------LERVRQWLKMDDLMEQERVMRQ 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3347	NP_001285579.1	PHD_SF	23..68	CDD:304600	23/44 (52%)
Cfp1	NP_572556.1	PHD_Cfp1	62..107	CDD:277028	23/44 (52%)
		zf-CXXC	178..218	CDD:251032	8/49 (16%)
		zf-CpG_bind_C	300..532	CDD:289071	51/283 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I2586
eggNOG	1	0.900	-	-		E1_KOG1632
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4178
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D463371at2759
OrthoFinder	1	1.000	-	-		FOG0003492
OrthoInspector	1	1.000	-	-		otm47268
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46174
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1383
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.990