Protein Alignment CG3347 and Dido1

DIOPT Version :10

• Sequence 1: NP_722887.2
• Gene: CG3347 / 33538
• FlyBaseID: FBgn0031513
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_780760.2
• Gene: Dido1 / 23856
• MGIID: 1344352
• Length: 2256
• Species: Mus musculus
• Alignment Length: 718
• Identity: 142/718 - (19%)
• Similarity: 219/718 - (30%)
• Gaps: 302/718 - (42%)

  Fly    22 VYCICRQSHINGFMICCDNCNEWFHGDCIGLPANIG----EQHDTYYCTECFRKNPLLK------ 76
            :||||||.|.|.||||||.|.|||||||:|:....|    ...:.|.|..|    .:|:
Mouse   266 LYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNC----TILQVQDETN 326

  Fly    77 --------------------CT-----YKKSPSTTGV-------------------------PKT 91
                                ||     .:||....|:                         |..
Mouse   327 GSATDEQDSGCRSVGADGTDCTSIGTVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGA 391

  Fly    92 PK----------------------------------TPKTPKTPKNPKTPKTPKNSKTPKTARII 122
            ||                                  :.|..||....|....|:....||.:
Mouse   392 PKCIGPGCSSVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKTKPKEKVKTKPEKFSLPKCS--- 453

  Fly   123 NSIGV-------------RQNP-------RRRSTFVQERPSEVPNPSRQS--------------- 152
            ..:|:             |:||       .|..|..:|...|...||..|
Mouse   454 VQVGIKISSVHKRLASEKRENPVKKVMLASRSETSGKEAACESSTPSWASDHNYNAVKPEKPEKP 518

  Fly   153 -----TKLQKAVNYENATEEPTEDAEKVDQK-------------PKKTAKKKNPKPEDKVTDDAQ 199
                 |.|.|::..:...|:.|..|..:.:|             |:....||.| |...:.  ..
Mouse   519 TALSPTLLSKSMKDDRRVEDRTMAAVTIPKKALPSASLVGRQTSPRNLVPKKLP-PYSNMA--GA 580

  Fly   200 KPAVEKLFES-KGTQCNMFRDW-SKYVPPENSKKRG-TCFTVFCQQLARSCSRYCCDECGNFTAI 261
            |||::||... |||...  |.| |..:...::::.| |..|...::|..|            .|:
Mouse   581 KPAIKKLPSGFKGTIPK--RPWPSATLSGTSARQAGPTPMTAASKKLPGS------------AAV 631

  Fly   262 TNVFALGLLPNMPAMKVAMGHVGLLLG-------------------------ND-----LTNN-- 294
            ..|....:..|:||...|.|.:|.:..                         ||     :|.|
Mouse   632 VGVTRKPMSANVPAASPAPGRLGPVSPAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEV 696

  Fly   295 -------QKSNKN-SEASESKTETKPK-----VKKPKSEGRKSRYRSPSSSLER----SPDVSRT 342
                   :|...| .:.::::.::|.:     :|.||::|...|......||.:    .|:  ..
Mouse   697 GKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRMKPE--EL 759

  Fly   343 AAKRPKLQEELPSSSSRSSR-KLVEESRSETER-----------------------HKAKHKTSK 383
            .:|...:..|.|:.|...|| ||:.||:..|.:                       ..|..|::.
Mouse   760 VSKELSMWTEKPTKSVIESRTKLLNESKKNTTKPETIPDMEDSPPVSDSEEQQESVRAAPEKSAA 824

  Fly   384 ----------KEKTSSQRAY--------------SLSPIPSPKSYRAARNTSETAPNSPVNLKKT 424
                      |:.||..||:              |....|:||..:.:.::.          |:.
Mouse   825 PLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASSK----------KED 879

  Fly   425 FKQKHVISSP-----TGKKRVCRSQTISADDP--------------LPSQPKSTEVSPMASAGTS 470
            ||.:|..|.|     |..:.:..:...:|.:|              .|..|..:...|.:..|.|
Mouse   880 FKPRHDSSPPNAVPNTADEGIADTLPENASEPDPESTSSLNQERKCFPESPGDSHPEPSSLGGLS 944

  Fly   471 SSN 473
            .|:
Mouse   945 PSS 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3347	NP_722887.2	PHD_SF	23..68	CDD:473978	26/48 (54%)
Dido1	NP_780760.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..256
		TNG2	<157..299	CDD:227367	23/32 (72%)
		Nuclear localization signal. /evidence=ECO:0000255	162..170
		Nuclear localization signal. /evidence=ECO:0000255	182..190
		PHD_DIDO1_like	263..316	CDD:277109	26/49 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..535		10/53 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..624		6/25 (24%)
		PRK14954	<600..>665	CDD:184918	15/76 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	641..668		6/26 (23%)
		TFS2M	669..770	CDD:128786	16/102 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	778..822		8/43 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	856..970		19/102 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1011..1039
		SPOC_DIDO1-like	1051..1193	CDD:439210
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1197..1218
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1245..1288
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1320..1347
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1362..1421
		SWIRM-assoc_1	<1462..1499	CDD:465142
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1509..1609
		PHA03247	<1571..2083	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1630..2256
		SF-CC1	2142..>2180	CDD:273721