Protein Alignment CG34393 and rasgef1a

DIOPT Version :10

• Sequence 1: NP_608753.2
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_012822158.1
• Gene: rasgef1a / 734010
• XenbaseID: XB-GENE-5739365
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 557
• Identity: 136/557 - (24%)
• Similarity: 216/557 - (38%)
• Gaps: 159/557 - (28%)

  Fly   177 SVLGS--------------GGIMYINGRIVSGPLDSLIETLLPKDVVDLDKEFVFSFLLSCRLFL 227
            |:|||              |..:|.:|.:|||.|:.|||.|:|......||.::|:||||.|:|:
 Frog    19 SMLGSTCSGQVQPEMGEHCGDPVYQDGSLVSGSLEVLIERLVPTLDYYPDKTYIFTFLLSARIFI 83

  Fly   228 RPHELLGRL----------LDSVPESECLE------SLVSLLAEWTMKFPYDYRDERMMSHVKHI 276
            .|:|:|.::          |:|..|::..:      .::.||.|||..||:|::|||....:|.|
 Frog    84 HPYEILAKVGQMCIKQKQQLESGSEADKAKLKSFAAKIIQLLREWTETFPFDFQDERARKEMKEI 148

  Fly   277 VARCS-----NSHLEAAVSQTLSALLKRLT---DLERHEADLR--------ACQTNDKSGPETPL 325
            ..|.:     |..::.::||....:|..|:   ..:.....:|        ..:|..:|..:..|
 Frog   149 AQRITQCDEENGTIKKSISQMTQNVLVVLSTRGQFQEVREKIRQPVSDKGTILKTKPQSAQKDIL 213

  Fly   326 N-CPTATQYAQIVCRVEKKLAKHIGGEEFLQ-CSSMILLDKQKKWDQPSTSGAPPGAQDPKKTCN 388
            : |......||.:..:|.:...:|..|:.:| .|.|..||..|            ...|..||.|
 Frog   214 SVCSDPLILAQQLTTIELERLGNIFPEDLMQIISHMDSLDNHK------------CRSDVTKTYN 266

  Fly   389 LETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESLESPAIAR 453
            ||.|.:|...|.:.|..||.:.|..:.|:|.:|.:..||:.|..:||:||..||:..:....:||
 Frog   267 LEAYDNWFNCLSMLVATEICKVVKKKQRTRVMEFFIDVARECFNIGNFNSMMAIISGMNLSPVAR 331

  Fly   454 LKITWSKLQVTCQQLDCMQRHAEGHGHLWQKQAISLNEQQEGLKTDKQAPKEPAAQGAAPTQGAV 518
            ||.||||::..  :.|.::.|.:
 Frog   332 LKKTWSKVKTA--KFDVLEHHMD------------------------------------------ 352

  Fly   519 AIAITTSSDSDEKPSTSGRVAGIAGISAATMESAPVPVASGSNVDAATAAAARTSTTAATTPLAS 583
                                                |.::..|.        ||:...||....|
 Frog   353 ------------------------------------PSSNFCNY--------RTALQGATQRSQS 373

  Fly   584 SGKPNDWVVIPVFADIVKLALGERENCLQRLANGHINMAAFDRMAAIVGAFTKHMQAMKAAQAPS 648
            :....:.:|||||...:|......:....||.|||||...|..::..:..|.    ..|..:.|
 Frog   374 ANSSREKIVIPVFNLFIKDIFFLHKIHSNRLPNGHINFKKFWEISRQIHDFL----TWKQVECP- 433

  Fly   649 SGEYE---HFCRHMQQTTKLGEAELMMASFDCEEPNN 682
               ||   ....::..|....|..|.:|||:.|.|:|
 Frog   434 ---YEKDKKIQTYLLTTPIYTEEALFLASFENEGPDN 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_608753.2	REM	196..300	CDD:100121	39/124 (31%)
		RasGEF	334..>473	CDD:459872	45/139 (32%)
rasgef1a	XP_012822158.1	REM	51..168	CDD:100121	36/116 (31%)
		RasGEF	222..415	CDD:459872	66/292 (23%)