Protein Alignment CG34393 and rapgef6

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001361718.1
• Gene: rapgef6 / 733941
• XenbaseID: XB-GENE-981546
• Length: 1644
• Species: Xenopus tropicalis
• Alignment Length: 489
• Identity: 89/489 - (18%)
• Similarity: 163/489 - (33%)
• Gaps: 151/489 - (30%)

  Fly    71 LELGESGADSREAGAGGGAGLQVAQGGIFSL-----------DPGHL--TAETAL-----LGGNI 117
            :|..|.|:.:.|||...|..:....|..|..           :..||  |.:|.:     |...|
 Frog   558 IESVEPGSKATEAGLKRGDQIMEVNGQNFETIVYAKALEILKNNTHLSITVKTNIFVFKELLNRI 622

  Fly   118 RYRRRHSAEQL-----------SAYDLEMGFQQL---------ELGTTISVGPKNE-----DLVQ 157
            ...:::....:           |..||....:|:         ....|:| |.:|.     |..:
 Frog   623 GQEKKNGVPHIPKIAEKKNNRYSIPDLPNDVEQMFPRDRASKKMKANTVS-GGRNRIRKILDKTR 686

  Fly   158 YDV-PKNPHKRSQCDINFESSVLG------SGGIMYINGRIVSGPLDSLIETLLPKDVVDLDKEF 215
            :.: |..|........:.:.|::|      |..||.|.|.:.|...|.|..|   .:::|.....
 Frog   687 FSILPPKPFSDGHVIQSQDDSIVGTRQCRHSVAIMPIPGTLSSSSPDLLQAT---TNILDFSNPT 748

  Fly   216 VFSFLL----SCRLFLRPHE----LLGRLLDSVPESECLESLVSLLAEWTMKFPYD--------- 263
            .|.|..    ..|:|....:    ::|:      ::...|.::..|.|:::....|
 Frog   749 AFGFYYIPDQVIRIFKADQQCCYIIIGK------DTTAKEVVIQALHEFSLTGSTDTYSLCEVSV 807

  Fly   264 -----YRDERMMSHVKHIVAR------------------CSNSHLEAAVSQTLSALLKRLTDLER 305
                 .:..|:...:..:..|                  ||:...:..:.::|.:||:..|....
 Frog   808 SPEGVIKQRRLPDQLSKLADRIQLNGRYYLKNNMETETLCSDEDAQELLRESLISLLQLSTIEVA 872

  Fly   306 HEADLRACQTNDKSGPETPLNCPTATQYAQIVCRVEKKL-AKHIGGEEFLQCSSMILLDKQKKWD 369
            .:..:|..:......|         |:|...:.:::.|. |.|:  ::|
 Frog   873 TQLSMRDFELFRNIEP---------TEYIDDLFKIDSKTSAAHL--KQF---------------- 910

  Fly   370 QPSTSGAPPGAQDPKKTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVG 434
                          ::..|.||:  |       |..|||:......|.:.|:.:...|.:|....
 Frog   911 --------------EEVINQETF--W-------VATEILREPNHLKRMKIVKHFIKTALHCRECR 952

  Fly   435 NYNSATAILESLESPAIARLKITWSKLQVTCQQL 468
            |:||..||:..|....:|||:.||.||....::|
 Frog   953 NFNSMFAIISGLNLAPVARLRGTWEKLPSKYEKL 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	20/143 (14%)
		RasGEF	334..>473	CDD:279011	30/136 (22%)
rapgef6	NP_001361718.1	CAP_ED	37..119	CDD:381773
		CAP_ED	280..380	CDD:237999
		RasGEFN	412..525	CDD:214571
		PDZ_signaling	528..609	CDD:238492	12/50 (24%)
		RA_PDZ-GEF1	758..840	CDD:340483	9/87 (10%)
		RasGEF	863..1097	CDD:214539	37/174 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910