Protein Alignment CG34393 and rasgrf2b

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_009300046.1
• Gene: rasgrf2b / 553520
• ZFINID: ZDB-GENE-060504-1
• Length: 1275
• Species: Danio rerio
• Alignment Length: 554
• Identity: 117/554 - (21%)
• Similarity: 181/554 - (32%)
• Gaps: 171/554 - (30%)

  Fly     6 YASKISAIACGTRCKQTVLQKSRGQRDRDKCHHGHHQHHRRHHRRRCR---------ISSNSSST 61
            |:.||..||. .:.|...|..:..|.:|.    |.|.:.:  ..|.||         |||.:||.
Zfish   710 YSLKIRKIAL-DQSKSLELFFATNQNNRS----GDHVNDK--SPRLCRKFSSPPPLSISSRTSSP 767

  Fly    62 DSESADECGLELGESGADSREAGAGGGAGLQVAQGGIFSLDPGHLTAETALLGGNIRYRRRHSAE 126
                            ..:|:.......|.:|   ||..|.....:|.::....|
Zfish   768 ----------------VRTRKLSLNSPIGSKV---GILDLSTTSSSAASSPTSAN---------- 803

  Fly   127 QLSAYDLEMGFQQLELGTTISVGPKNE--------DLVQYDVPKNPHKRSQCDINFESSVLGSGG 183
                             .|||..|.|.        ||.:...|.:|.:              |.|
Zfish   804 -----------------PTISPPPSNNNNNSKPPLDLSRGQSPSSPEQ--------------SPG 837

  Fly   184 IMYINGRI-----VSGPLDSLIETLLPKDVVDLDKEFVFSFLLS-------CRLFLRPHELLGRL 236
            .:..|..:     :.|.|...|...: .:.|.|||....|...|       ||....|..|..|.
Zfish   838 ALDDNAEVPRIDALCGKLRRSIRRAV-LESVSLDKFIPESPQASEPGEISPCRSPSTPRHLRYRQ 901

  Fly   237 --LDSVPESECLESLVSLLA-----------------EWTMKFPYDYR---DERMMSHVKHIVAR 279
              :.:...|.|..|..|..|                 |.|....:..|   ..|:::.::|.|::
Zfish   902 SGVQTAENSRCSVSPASAFAIATAAAGHSSPPVFNNSERTCDKEFIIRRAATNRVLNVLRHWVSK 966

  Fly   280 CS-----NSHLEAAVSQTLSALLKRLTDLERHEAD-----LRACQTNDKSGPETPL-------NC 327
            .|     |..|:..|...|..:| |..||...|..     |.|...:|:...:..:       .|
Zfish   967 HSQDFEMNGELKMGVICLLEEVL-RDPDLLPQERKATANILSALSQDDQDDAQLKIEDILQMAEC 1030

  Fly   328 P--------TATQYAQIVCRVEKKLAKHIGGEEFLQCSSMILLDKQKKWDQPSTSGAPPGAQDPK 384
            |        :|.:.|:.:..::..:.:.|..||||          .:.|.:...:...|......
Zfish  1031 PKAECFESLSAMEIAEQITLLDHIVFRSIPYEEFL----------GQGWMKTDKTERTPYIMKTS 1085

  Fly   385 KTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESLESP 449
            :..|     |.|.    .|.::|:....:..|:.::|.|..||..|..:.|||....|..:|...
Zfish  1086 QHFN-----DMSN----LVASQIMSHTDVGSRAGSIEKWVAVADICRCLNNYNGVLEITSALNRS 1141

  Fly   450 AIARLKITWSKLQVTCQQ----LDCMQRHAEGHG 479
            ||.|||.||:|:   |:|    :|.:|:.....|
Zfish  1142 AIYRLKKTWAKV---CKQTKALMDKLQKTVSSEG 1172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	30/137 (22%)
		RasGEF	334..>473	CDD:279011	35/142 (25%)
rasgrf2b	XP_009300046.1	PH_RasGRF1_2	19..154	CDD:270081
		PH	24..129	CDD:278594
		RhoGEF	243..424	CDD:279015
		PH	476..584	CDD:214574
		PH	476..583	CDD:278594
		RasGEF_N	634..>682	CDD:279012
		REM	<938..1010	CDD:295342	18/72 (25%)
		RasGEF	1036..1272	CDD:214539	38/159 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910