Protein Alignment CG34393 and rasgef1b

DIOPT Version :10

• Sequence 1: NP_608753.2
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_031756070.1
• Gene: rasgef1b / 549667
• XenbaseID: XB-GENE-1015760
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 575
• Identity: 143/575 - (24%)
• Similarity: 228/575 - (39%)
• Gaps: 149/575 - (25%)

  Fly   150 PKNEDLVQYD-----VPKNPHKRSQCDIN------FESSVLGSGGIMYINGRIVSGPLDSLIETL 203
            |..:.|  ||     :|:.|...:..|.:      ::|.......:.|.:..::||.|::||:.|
 Frog   103 PSEKSL--YDPVLERMPQTPTLVAMFDSSSFHRNLYQSKEESCSELYYQDNNLLSGSLEALIQHL 165

  Fly   204 LPKDVVDL--DKEFVFSFLLSCRLFLRPHELLGRL--------------LDSVPESECLESLVSL 252
            :|.  ||.  |:.::|:||||.|||:.|.||:.|:              ||.....:....::.|
 Frog   166 VPN--VDYYPDRTYIFTFLLSSRLFIHPSELMARVCHVCMEQQRLNEPGLDKSQVRKIAPKILQL 228

  Fly   253 LAEWTMKFPYDYRDERMMSHVKHIVARCSNSH--LEAAVSQTLSALLKRLTDLERHEADLRA--C 313
            |.|||..||||:||||||.::|....|.:|..  ....|.|.:..|:::|..|.::|..:..  .
 Frog   229 LTEWTETFPYDFRDERMMRNLKDTAHRITNGDEMYRKNVQQIIQNLIRKLASLTQYEELITKINA 293

  Fly   314 QTND-----KSGPETPLN-----CPTATQYAQIVCRVEKKLAKHIGGEEFLQCSSMILLDKQKKW 368
            |:.|     |:.|::...     |......||.:..:|.:...:||.|||:|  :.:..|.....
 Frog   294 QSTDRMTVLKTKPQSIQRDIITVCSDPYTVAQQLTHIELERLSYIGPEEFVQ--AFVQKDPLDNN 356

  Fly   369 DQPSTSGAPPGAQDPKKTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLV 433
            :|...|       |.||..|||.|::|..||...|..||...|..:.|:|.:|.:..||:.|..:
 Frog   357 EQNCYS-------DRKKPRNLEAYVEWFNRLSYLVATEICMPVKKKHRARMIEFFIDVARECFNI 414

  Fly   434 GNYNSATAILESLESPAIARLKITWSKLQVTCQQLDCMQRHAEGHGHLWQKQAISLNEQQEGLKT 498
            ||:||..||:..:....::|||.||:|::..  :.|.::...:
 Frog   415 GNFNSLMAIISGMNMSPVSRLKKTWAKVKTA--KFDILEHQMD---------------------- 455

  Fly   499 DKQAPKEPAAQGAAPTQGAVAIAITTSSDSDEKPSTSGRVAGIAGISAATMESAPVPVASGSNVD 563
                                                                    |.::..|..
 Frog   456 --------------------------------------------------------PSSNFYNYR 464

  Fly   564 AATAAAARTSTTAATTPLASSGKPNDWVVIPVFADIVKLALGERENCLQRLANGHINMAAFDRMA 628
            .|...||:.|.||.:.        .:.:|||..:.::|......|.|..||.|||:|...|..:|
 Frog   465 TALRGAAQRSLTAHSN--------REKIVIPFCSLLIKDIYFLNEGCTSRLPNGHVNFEKFWELA 521

  Fly   629 AIVGAFTKHMQAMKAAQAPSSGEYEHFCRHMQQTTKL-GEAELMMASFDCEEPNN 682
            ..|..|    ...|..:.|.  |.:....|...|..: .|..|.:||::.|.|.|
 Frog   522 KQVSEF----MTWKQVECPF--EKDRKILHYVLTAPIFSEDALYLASYESEGPEN 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_608753.2	REM	196..300	CDD:100121	43/121 (36%)
		RasGEF	334..>473	CDD:459872	45/138 (33%)
rasgef1b	XP_031756070.1	REM	157..281	CDD:100121	44/125 (35%)
		RasGEF	323..518	CDD:459872	65/291 (22%)