Protein Alignment CG34393 and Rgl

DIOPT Version :10

• Sequence 1: NP_608753.2
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001261814.1
• Gene: Rgl / 44115
• FlyBaseID: FBgn0026376
• Length: 973
• Species: Drosophila melanogaster
• Alignment Length: 575
• Identity: 102/575 - (17%)
• Similarity: 175/575 - (30%)
• Gaps: 216/575 - (37%)

  Fly    25 QKSRGQRDRDKCHHGHHQHHRRHHRRRCRISSNSSSTDSESADECGLELGESGADSREAGAGGGA 89
            |:.:.|:.:|......|.||....|:|     ..|.|..|....|..........||.|.|
  Fly    73 QRQQQQQQQDAKDSKRHYHHHTCPRQR-----KKSMTPVEPTHLCQKHQEAKQRRSRSASA---- 128

  Fly    90 GLQVAQGGIFSLDPGHLTAETALLGGNIRYRRRHSAEQLSAYDLEMGFQQLE------------- 141
                                        :.||..|.......|:.......|
  Fly   129 ----------------------------KPRRNSSYHSYDDLDVSSAVLNAERKVVASLKYLCAC 165

  Fly   142 LGTTI-SVGPKNEDL-------------------------------VQYDVPKNPHKRSQCD--- 171
            .|.|: ::..|.:||                               |:|..| .|...:..|
  Fly   166 TGATLRNLSKKTKDLHAKNYTYTKPTWRLWGEEHEKNAIFTVYLKKVRYHRP-TPTASNDSDDEI 229

  Fly   172 --INFESSVLGSGGIMYINGRIV-SGPLDSLIETLLPKDVVDLDKEFVFSFLLSCRLFLRPHELL 233
              :.:|:          :..|.| :..|..|:|.|...| .:|:..|:..||.:.|.|..|.::|
  Fly   230 SHLEWET----------VRVRFVKAATLARLVEALATDD-GELESTFINVFLSTYRTFSTPKQVL 283

  Fly   234 ------------------------GRLLD-------SVPESECLESLVSLLAEWTMKFPYDYRDE 267
                                    |:::|       |:.|.. .::|||.|..|...||.|:.::
  Fly   284 SLLTQRYDALHEKHLEELEQAQQNGQVMDPAYDPHASIHEQH-KKTLVSALHVWLDGFPEDWHED 347

  Fly   268 RMMSHVKHIVARCSNSHLEAAVSQTLSALLKRL----------TDLERHE--ADLRACQ------ 314
            .:...:.....|...|.|...|...|..|:|:.          ::...|.  :..|:.|
  Fly   348 NLQQILAFATKRLKRSDLHIKVLNRLERLIKQSLYGNGGGSGGSENNGHSWLSAARSQQMQQFMI 412

  Fly   315 ----------TNDKSG------------------------PETPLNCPTATQYAQIVCRVE---- 341
                      |:..:|                        |..|:.     .:|:.:.|::
  Fly   413 PTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPTHFLQAFRFPHVPVR-----HFAEQLTRMDTELF 472

  Fly   342 KKLAKHIGGEEFLQCSSMILLDKQKKWDQPSTSGAPPGAQDPKKTCNLETYLDWSARLRLFVCNE 406
            |:|..|       ||..       ..|.:..:.|:        :|. :.|...::|.|...|.:.
  Fly   473 KRLIPH-------QCLG-------HTWARRDSGGS--------ETV-VATINQFNAVLFRVVSSI 514

  Fly   407 ILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESLESPAIARLKITWSKL 461
            ::..:..:.|:..:..|..:||...::.|::|..||:.:|.|.:|.||...|..|
  Fly   515 LIDRLKPQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKIWEVL 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_608753.2	REM	196..300	CDD:100121	32/134 (24%)
		RasGEF	334..>473	CDD:459872	29/132 (22%)
Rgl	NP_001261814.1	REM	246..378	CDD:100121	31/133 (23%)
		RasGEF	454..719	CDD:214539	30/144 (21%)
		RA_RalGDS_like	858..946	CDD:340449