DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34393 and CG5522

DIOPT Version :9

Sequence 1:	NP_001285578.1	Gene:	CG34393 / 33534	FlyBaseID:	FBgn0085422	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_725613.1	Gene:	CG5522 / 36881	FlyBaseID:	FBgn0034158	Length:	702	Species:	Drosophila melanogaster

Alignment Length:	218	Identity:	44/218 - (20%)
Similarity:	77/218 - (35%)	Gaps:	47/218 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 EQQEGLKTDKQAPKEPAAQGAAPTQGAVAIAITTSSDSDEKPSTSGRVAGIAGISAATMESAPVP 555
            :||:..:..||  :.|...|:|.|...:....|......|.||...:.:....|.:...:::...
  Fly    54 QQQQPTRVSKQ--RSPNTNGSAHTMACLRQEKTYKEQQMEPPSMQPQASKTLNIKSTRRKNSIGC 116

  Fly   556 VAS-GSNVDA-----ATAAAARTSTTAATTPLASSGKPNDWVVI-------------------PV 595
            :.| .|:.|:     ..||:|...:.:.:.|..:|.|..|.|::                   ||
  Fly   117 LNSFSSSPDSPGCYYTIAASAAPPSKSQSLPAHASIKQLDAVILSALRVPADVLANQITLLDFPV 181

  Fly   596 FADIVKLALGERENCLQRLANGHINMAAFDRMAAIVGAFTKH---------MQAMKAAQAPSSGE 651
            ||.|..   .|..:|.....:.|:|       ...:.||||.         .:.:.|.|.....|
  Fly   182 FAQIQP---DELSSCAWTKKDKHVN-------TPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAE 236

  Fly   652 -YEHFCRHMQQTTKLGEAELMMA 673
             ..||.:..::..:|.....:.|
  Fly   237 IITHFIKVAKKLHELNNLHSLFA 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121
CG34393	NP_001285578.1	RasGEF	334..>473	CDD:279011
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	20/107 (19%)
		PH_RalGPS1_2	578..692	CDD:270120
		PH	578..685	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010