Protein Alignment CG34393 and Rapgef5

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001360918.1
• Gene: Rapgef5 / 217944
• MGIID: 2444365
• Length: 879
• Species: Mus musculus
• Alignment Length: 620
• Identity: 111/620 - (17%)
• Similarity: 179/620 - (28%)
• Gaps: 231/620 - (37%)

  Fly    30 QRDRDKCHHGHHQHHRRHHRRR------------------CRISSNSSSTDSESADE-------- 68
            |...|:|.:.:.:..|....::                  |.:|...:....||:||
Mouse   180 QFSSDECSYLYCEFEREEEWQKGVKLLLELVHLIPARAGICDLSHQKTEDSEESSDEILARLTSA 244

  Fly    69 ---------------CGLELGESGADSREAGAGGGAGLQVAQGGIFSL----DPGHLTAETALLG 114
                           ..:|..:..||..........|.....|.:..|    |.|.:.....|..
Mouse   245 VQRELAAVIALKARKSAIEQDDENADKHVTVTEANNGPDPQAGVMCKLQERDDIGRIELVHKLAR 309

  Fly   115 GNIRY--RRRHSAEQLSAYDLEMGFQQL-ELGTTI-------SVGPKNEDLVQYDVPKNPHKRSQ 169
            .|.::  ..:..:|:|...|.|:...|: |.|.::       |.||.
Mouse   310 ENCQFLQTEKKESEKLEQQDDEVTMVQVKEQGQSVLVLKKVASCGPA------------------ 356

  Fly   170 CDINFESSVLGSGGIMYINGRIVSGPLDSLIETLL---------PKDVVDLDKEFVFSFLL---- 221
                 .:|........|:   :|||..:.::|.||         .|:...|..:|:.::.:
Mouse   357 -----PTSGSAENDARYV---VVSGTPEKILEHLLNDLHLAEVQHKETETLLDDFLLTYTVFMTT 413

  Fly   222 --SCRLFLRP-------------------------------------HE----------LLGRLL 237
              .|:..||.                                     ||          :...:|
Mouse   414 DDLCQALLRHYSAKKYQGEEENSDVPCRKRKVLHLVSQWISLYKDWLHEDEHSKMFLKTIYRNVL 478

  Fly   238 DSVPESECLESLV-------------------------------SLLAEWTMKFPYDYRDERMMS 271
            |.|.|...||..:                               ||...|..........|.:..
Mouse   479 DDVYEYPILEKELKEFQKILGVYRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVAETEEIFC 543

  Fly   272 HVKHIVARCSNSHLEAAVSQTLSALLKRLTD-LERHEADL-----------RACQTNDKSGPETP 324
            ||  .:...|...::|.||.|...:||.:.: |:|.|.||           ...|.||
Mouse   544 HV--YITEHSYISVKAKVSSTAQEILKVVAEKLQRAEEDLALVAITFSGEKHEFQPND------- 599

  Fly   325 LNCPTATQYAQIVCRVEKKLAKHIG----GEEFLQCSSMILLDKQKKWDQP-------------- 371
            |....:.:.:..:....|.||..:.    .||..|.|..||  ....||..
Mouse   600 LAISKSLEASGRIYVYRKDLADTLNPLAENEESQQRSMRIL--GMNTWDLALELMSFDWSLFNSI 662

  Fly   372 ----------STSGAPPGAQDPKKTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGV 426
                      |..|      :.:.|.||...|.....::|:|..|||....:..|.:.|:.:..:
Mouse   663 HEQELIYFTFSRQG------NGENTVNLSLLLQRCNEVQLWVATEILLCSQLGKRVQLVKKFIKI 721

  Fly   427 AQYCLLVGNYNSATAILESLESPAIARLKITWSKL 461
            |.:|....|.||..||:..|.:.:::||..||.|:
Mouse   722 AAHCKAQQNLNSFFAIVMGLNTASVSRLSQTWEKI 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	30/196 (15%)
		RasGEF	334..>473	CDD:279011	37/156 (24%)
Rapgef5	NP_001360918.1	DEP_Epac	98..221	CDD:239884	4/40 (10%)
		RasGEFN	367..498	CDD:214571	21/133 (16%)
		RasGEF	639..878	CDD:214539	30/126 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910