Protein Alignment CG34393 and R05G6.10

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001294201.1
• Gene: R05G6.10 / 177527
• WormBaseID: WBGene00019902
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 112/560 - (20%)
• Similarity: 209/560 - (37%)
• Gaps: 164/560 - (29%)

  Fly   165 HKRSQCDINFESSVLGSGGIMYINGRIVSGPLDSLIETLLPKDVVDLDKEFVFSFLLSCRLFLRP 229
            ||..    .||.:.|    ::...|.::||..|:||..|:|......|:.::||.|::.|.|:.|
 Worm   102 HKSD----TFEQNDL----VLDNTGAVLSGSRDALIRRLVPTRDFCPDESYIFSLLVNIRTFISP 158

  Fly   230 HELLGRLLDSVPESECLES--------------LVSLLAEWTMKFPYDYRDERMMSHVKHIVARC 280
            |||:.:::.....::..:|              ::.|.:||....|||::.|.|.:.:..::..|
 Worm   159 HELMQKIVQYCMFAQNADSHNFAKEGRGRMFAHILRLCSEWATNIPYDFKTEYMRTRLNELLRLC 223

  Fly   281 S-NSHLEAAVSQTLSALLKRLTDLERHE---ADLRACQTNDKSGPETP-------LNCPTATQYA 334
            : :...:...::..|.|...|..|:|:|   |:|:...:.:.:.||..       :.|..|...|
 Worm   224 AVDKTYQQKTTELQSTLRSSLNKLDRYEKAVANLQKALSENTNLPEQSDSMTGLFVLCNDAKTVA 288

  Fly   335 QIVCRVEKKLAKHIGGEEFLQ---CSSMILLDKQKKWDQPSTSGAPPGAQDPKKTCNLETYLDWS 396
            |.:..:|.:....:|.:|.:|   ...:..:.:..|..:.:.|             ::..|::|.
 Worm   289 QQLTHIEMERFSMVGVDEIVQSLASDPLSEIGRHSKNKEGTIS-------------SISFYIEWF 340

  Fly   397 ARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESLESPAIARLKITWSKL 461
            .||..|...|:|:......|....|....:|:.|..:||:||..||:..|..||::|||.||.::
 Worm   341 NRLSAFAAIEVLKQTKKRNRVAVFEFMIDIAKECCEIGNFNSMMAIVAGLSLPAVSRLKKTWCRV 405

  Fly   462 QVTCQQLDCMQRHAEGHGHLWQKQAISLNEQQEGLKTDKQAPKEPAAQGAAPTQGAVAIAITTSS 526
            :..  :|:.:|...:..|:....:|
 Worm   406 EKA--KLEILQHQLDPSGNFLSYRA---------------------------------------- 428

  Fly   527 DSDEKPSTSGRVAGIAGISAATMESAPVPVASGSNVDAATAAAARTSTTAATTPLASSGKPNDW- 590
                                                           |..|....|.|.:.|..
 Worm   429 -----------------------------------------------TIKAAQWRADSARGNQQK 446

  Fly   591 VVIPVFADIVKLALGERENCLQRLANGHINMAAFDRMA----------AIVGAFTKHMQAMKAAQ 645
            :|||.|..::|..........:.|.|.|:|..||:::|          :.|..|.|:.|.:
 Worm   447 IVIPFFVLLLKDLFLIYHGHPRILPNAHLNFMAFNQLAEQLRDVIQWKSTVCTFEKNPQVL---- 507

  Fly   646 APSSGEYEHFCRHMQQTTKLGEAELMMASFDCEEPNNAEK 685
                       :::..|:..||.:.|:.||:||.|.::.:
 Worm   508 -----------QYLLITSVSGEKDSMLMSFECEPPESSSE 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	27/118 (23%)
		RasGEF	334..>473	CDD:279011	34/141 (24%)
R05G6.10	NP_001294201.1	RasGEFN	116..242	CDD:214571	30/125 (24%)
		RasGEF	279..532	CDD:214539	68/369 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3541
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3112
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D246323at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.870