DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34393 and AgaP_AGAP004853

DIOPT Version :9

Sequence 1:	NP_001285578.1	Gene:	CG34393 / 33534	FlyBaseID:	FBgn0085422	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	XP_314338.4	Gene:	AgaP_AGAP004853 / 1275114	VectorBaseID:	AGAP004853	Length:	674	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	58/282 - (20%)
Similarity:	101/282 - (35%)	Gaps:	63/282 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 RPHELLGRLLDSVPESECLESLVSLLAEWTMKFPYDYRDERMMSHVKHIVARCSNSHLEAAVSQT 292
            :|::...:.||.        |:.:.|.|...:.|..:||.:  ...||:..:.:...:|:
Mosquito    61 QPNQHAEKALDG--------SIDTPLIEDGKRKPERHRDRQ--PDDKHLCHKATAGSIES----- 110

  Fly   293 LSALLKRLTDLERHEADLRACQTNDKSGPETPLNCPTATQYAQIV--CR-------------VEK 342
                   |.|.....:..|...:..|.....|.| .|.:....||  |:             ::.
Mosquito   111 -------LNDGCSATSSFRPWHSYSKKSYSLPPN-TTISDVGSIVFSCQQVSPAELAAQITLLDF 167

  Fly   343 KLAKHIGGEEFLQCSSMILLDKQKKWDQPSTSGAPPGAQDPKKTCNLETYLDWSARLRLFVCNEI 407
            .:...|..||...|.          |.:.:.....|......|..|..|:  |:.:       ||
Mosquito   168 PIFNAIQPEELTSCG----------WTKKNKHTLAPNVVAFTKRFNHTTF--WTVQ-------EI 213

  Fly   408 LQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESLESPAIARLKITWSKLQVT---CQQLD 469
            |..|..:.|:..:..:..||:....:.|.:|..|::.:|:|.::.|||.:|  |.|:   .||||
Mosquito   214 LNGVSPKDRAEIISHFIKVAKKLHDINNLHSLFAVISALKSASVHRLKESW--LLVSRKDQQQLD 276

  Fly   470 CMQRHAEGHGHLWQKQAISLNE 491
            .:. |.......|......||:
Mosquito   277 RLS-HLFDESDNWSSLRKCLNQ 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	12/71 (17%)
CG34393	NP_001285578.1	RasGEF	334..>473	CDD:279011	35/156 (22%)
AgaP_AGAP004853	XP_314338.4	RasGEF	152..389	CDD:214539	36/168 (21%)
		PH_RalGPS1_2	547..660	CDD:270120
		PH	549..655	CDD:278594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910