Protein Alignment CG34393 and AgaP_AGAP000614

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_310467.4
• Gene: AgaP_AGAP000614 / 1271618
• VectorBaseID: AGAP000614
• Length: 839
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 162/711 - (22%)
• Similarity: 244/711 - (34%)
• Gaps: 232/711 - (32%)

  Fly    59 SSTDSESADECGLELGESGADSREAGAGGGAGLQVAQGGIF---SLDPGHLTAETALLGGNIRYR 120
            ||...|..:..|.......||.  .|.|.|||....|...:   |:|.|..| ||
Mosquito   178 SSRTVEMTEGIGGSYQRGVADG--GGGGAGAGRLANQKRCWPSGSVDSGQWT-ET---------- 229

  Fly   121 RRHSAEQLSAYDLEMGFQQLELGTTI--SVGPKNEDLVQYDVPKNPHKRSQCDINFESSVLGSGG 183
                       |.....:|    ||:  ::..|.:||:
Mosquito   230 -----------DAPPEVRQ----TTVDPALYAKADDLL--------------------------- 252

  Fly   184 IMYINGRIVSGPLDSLIETLLPKDVVDLDKEFVFSFLLSCRLFLRPHELLGRLLDSVPESECLES 248
            :.|..|.::||.|:.|:....|......|:.|:|:|||:.|.||||.|:|.|.|.:...:....:
Mosquito   253 LHYTEGNLISGTLEGLLTHFTPTGSYLPDRSFIFTFLLAARQFLRPDEILERTLRAAISNGGTAN 317

  Fly   249 LVSLLAEWTMKFPYDYRDERMMSHVKHIVARCS--------------------NSHLEAAVSQTL 293
            |..|||.|...||||:||||||..|:....:.|                    .:...:.:|:.|
Mosquito   318 LPHLLAAWMNDFPYDFRDERMMRLVRSFTEQQSAGGGGPPPPTGRPHDPPDRGKARERSTLSRAL 382

  Fly   294 SALLKRLTDLERHEADLRACQTNDKSGPETP------------------LNCPTATQYAQIVCRV 340
            ..|..||..|||:|.:         .||..|                  |...:....|..:..:
Mosquito   383 RRLAHRLAKLERYEVE---------KGPLGPPAKGGGLDDWKTAPALVELASGSPVLMANTLTAI 438

  Fly   341 EKKLAKHIGGEEFLQCSSMILLDKQKKWDQPSTSGAPPGAQDPKKTC---------NLETYLDWS 396
            |.:....||.|||.                      ||..|....:|         ||..|:.|.
Mosquito   439 EAERFSFIGLEEFF----------------------PPSGQSAGASCYRGTGPTGSNLLAYVQWY 481

  Fly   397 ARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESLESPAIARLKITWSKL 461
            .||...|..:||:|.....|:|.||.|....:.|...||:||..||:.:|....|.|||.||:|:
Mosquito   482 NRLTYVVATDILRSPRKRHRARAVEFWIETGRECFNRGNFNSLMAIIATLTGGPIGRLKKTWTKV 546

  Fly   462 QVTCQQL------DCMQRHAEGHGHLWQ---------KQAISLNEQQEGLKTDKQAPKEPAAQGA 511
            ..:...|      ..|...|.|.|:...         :|.:::.|.|                 |
Mosquito   547 TSSSSSLLSGMTSSSMISSASGIGNSSSTCSSAAGGGRQQLAILEHQ-----------------A 594

  Fly   512 APTQGAVAIAITTSSDSDEKPSTSGRVAGIAGISAATMESAPVPVASGSNVDAATAAAARTSTTA 576
            .||........|                    :.||...|.|....|.|...::::.::|.:::.
Mosquito   595 DPTNNFATYRAT--------------------LHAAAWRSCPASARSSSTSSSSSSKSSRHNSSC 639

  Fly   577 ATT----PLASSGKPNDWVVIPVFADIVK----------------------------LALGEREN 609
            ::.    | .|:.|.:...|:|.|:.::|                            |......:
Mosquito   640 SSDDGQGP-TSAKKGSAVAVLPFFSLLLKDLHFLNETSGNRFSDPYSKYHSFISLLILVTNCPFS 703

  Fly   610 CLQRLANGHINMAAFDRMAAIVGAFTKHMQAMKAAQAPSSGEYEHFCRHMQQTTKLGEAEL 670
            |...|.|||||   ||:...:    .:.:..::..|..||  |:..||..::...:..||:
Mosquito   704 CRCSLPNGHIN---FDKWRQL----GERLSEVRRWQRQSS--YQRRCRVGRRHKSVTSAEV 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	38/123 (31%)
		RasGEF	334..>473	CDD:279011	43/153 (28%)
AgaP_AGAP000614	XP_310467.4	REM	264..348	CDD:100121	34/83 (41%)
		RasGEF	431..719	CDD:279011	77/350 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3541
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770