Protein Alignment CG34393 and Rasgef1b

DIOPT Version :10

• Sequence 1: NP_608753.2
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_017454918.1
• Gene: Rasgef1b / 100361238
• RGDID: 1562220
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 565
• Identity: 141/565 - (24%)
• Similarity: 232/565 - (41%)
• Gaps: 145/565 - (25%)

  Fly   160 VPKNPHKRSQCDIN------FESSVLGSGGIMYINGRIVSGPLDSLIETLLPKDVVDL--DKEFV 216
            :|:.|...:..|.:      ::.|....||:.|.:..::||.|::||:.|:|.  ||.  |:.::
  Rat     8 MPQTPPFSAMFDSSGYNRNVYQPSEDSCGGLNYHDNNLLSGSLEALIQHLVPN--VDYYPDRTYI 70

  Fly   217 FSFLLSCRLFLRPHELLGRLLDSVPESECLE--------------SLVSLLAEWTMKFPYDYRDE 267
            |:||||.|||:.|:||:.::.....|.:.|.              .::.||.|||..||||:|||
  Rat    71 FTFLLSSRLFMHPYELMAKVCHLCIEHQRLSEGDGDKNQTRKIAPKILQLLTEWTETFPYDFRDE 135

  Fly   268 RMMSHVKHIVARCSNSHLEA---AVSQTLSALLKRLTDLERHE---ADLRACQTND----KSGPE 322
            |||.::|.:..|.::...:.   .|.|.:..|:::|..|.::|   |.|.:..|:.    |:.|:
  Rat   136 RMMRNLKDLAHRMASGEEQTYRKNVQQMMQCLIRKLAALSQYEEVLAKLSSTATDRLTVLKAKPQ 200

  Fly   323 TPLN-----CPTATQYAQIVCRVEKKLAKHIGGEEFLQC-SSMILLDKQKKWDQPSTSGAPPGAQ 381
            :...     |......||.:..:|.:...:||.|||:|. .....||..|..           ..
  Rat   201 SIQRDIMTVCSDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKNC-----------YS 254

  Fly   382 DPKKTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESL 446
            :.|||.|||.|::|..||...|..||...|..:.|:|.:|.:..||:.|..:||:||..||:..:
  Rat   255 ERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGM 319

  Fly   447 ESPAIARLKITWSKLQVTCQQLDCMQRHAEGHGHLWQKQAISLNEQQEGLKTDKQAPKEPAAQGA 511
            ....::|||.||:|::..  :.|.::...:
  Rat   320 NMSPVSRLKKTWAKVKTA--KFDILEHQMD----------------------------------- 347

  Fly   512 APTQGAVAIAITTSSDSDEKPSTSGRVAGIAGISAATMESAPVPVASGSNVDAATAAAARTSTTA 576
                                                       |.::..|...|...||:.|.||
  Rat   348 -------------------------------------------PSSNFLNYRTALRGAAQRSLTA 369

  Fly   577 ATTPLASSGKPNDWVVIPVFADIVKLALGERENCLQRLANGHINMAAFDRMAAIVGAFTKHMQAM 641
            .::        .:.:|||.|:.::|......|.|:.||.|||:|...|..:|..|..|    ...
  Rat   370 HSS--------REKIVIPFFSLLIKDIYFLNEGCVNRLPNGHVNFEKFWELAKQVSEF----MTW 422

  Fly   642 KAAQAPSSGEYEHFCRHMQQTTKLGEAELMMASFDCEEP-NNAEK 685
            |..:.|...: ....:::.......|..|.:||::.|.| ||.||
  Rat   423 KQVECPFERD-RKVLQYLLSVPVFSEDALYLASYESEGPENNIEK 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_608753.2	REM	196..300	CDD:100121	41/122 (34%)
		RasGEF	334..>473	CDD:459872	45/139 (32%)
Rasgef1b	XP_017454918.1	REM	49..174	CDD:100121	42/126 (33%)
		RasGEF	216..410	CDD:459872	66/292 (23%)