DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15403 and FAM210B

DIOPT Version :9

Sequence 1:	NP_608749.2	Gene:	CG15403 / 33527	FlyBaseID:	FBgn0031504	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_543011.2	Gene:	FAM210B / 116151	HGNCID:	16102	Length:	192	Species:	Homo sapiens

Alignment Length:	137	Identity:	65/137 - (47%)
Similarity:	85/137 - (62%)	Gaps:	10/137 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 TKHGGCFKQNYSTESASTGTATT-------LKITKREQLKRAFKEYGATIVVFHVVISVISLGGF 126
            |..|.|  :.:...|.:|||..:       .|.:|.:|||:.|:|||...|..|:.||:||||.|
Human    53 TARGDC--RGHQDPSQATGTTGSSVSCTEEKKQSKSQQLKKIFQEYGTVGVSLHIGISLISLGIF 115

  Fly   127 YALVSSGINLVPVLEYFGMGSSAVAEKVAAG-STFVVAFAVHKIFAPARISITLGTTPFIVRYLR 190
            |.:||||:::..:|...|...|.|..|:||| ||||||:|:||:|||.||||||.:.|.||||.|
Human   116 YMVVSSGVDMPAILLKLGFKESLVQSKMAAGTSTFVVAYAIHKLFAPVRISITLVSVPLIVRYFR 180

  Fly   191 SKGLLKP 197
            ..|..||
Human   181 KVGFFKP 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15403	NP_608749.2	DUF1279	98..184	CDD:284361	47/86 (55%)
FAM210B	NP_543011.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	57..80		5/24 (21%)
FAM210B	NP_543011.2	DUF1279	87..174	CDD:284361	47/86 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152555
Domainoid	1	1.000	93	1.000	Domainoid score	I7556
eggNOG	1	0.900	-	-		E1_KOG4526
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4857
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1506373at2759
OrthoFinder	1	1.000	-	-		FOG0004761
OrthoInspector	1	1.000	-	-		otm40952
orthoMCL	1	0.900	-	-		OOG6_103781
Panther	1	1.100	-	-	LDO	PTHR21377
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4368
SonicParanoid	1	1.000	-	-		X4449
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790