Protein Alignment CG17221 and CRYZL1

DIOPT Version :10

• Sequence 1: NP_608746.1
• Gene: CG17221 / 33521
• FlyBaseID: FBgn0031500
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_665857.2
• Gene: CRYZL1 / 9946
• HGNCID: 2420
• Length: 349
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 78/358 - (21%)
• Similarity: 135/358 - (37%)
• Gaps: 112/358 - (31%)

  Fly    52 MRGWQLHNYGDIDEL----QLSEMLKIPQIRCSNECLVRIRATAVNPIDLAMLRGYGATVLNKMR 112
            |:|.........:|:    |..|.|.:.:   .|...::::|.|::.|:..:|.        :|:
Human     1 MKGLYFQQSSTDEEITFVFQEKEDLPVTE---DNFVKLQVKACALSQINTKLLA--------EMK 54

  Fly   113 CQPGDGIEFPLILGREFCGELVQTGMGVSL--PLGSRVWGVVPLQATIGSHAEYVAVPSYCLAPA 175
            .:..   .||  :|||..|.::..|..||.  | ...|.|::||.:......|.|.|..:.|...
Human    55 MKKD---LFP--VGREIAGIVLDVGSKVSFFQP-DDEVVGILPLDSEDPGLCEVVRVHEHYLVHK 113

  Fly   176 PKELDDYEAASVLYAGLTAWSGLYITGGLGGPCGATTASGGGAHKRVLVLGGSGGVGTLAIQILK 240
            |:::...|||..:..|:.|::.|:....|         |.|   |.||::.|:...||:|||:..
Human   114 PEKVTWTEAAGSIRDGVRAYTALHYLSHL---------SPG---KSVLIMDGASAFGTIAIQLAH 166

  Fly   241 SQKVQVLAT-CS----------------------------ENAIEMVRNLGADLVVDY------- 269
            .:..:|::| ||                            |:.:|....||.|:|:|.
Human   167 HRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKVHVAESCLEETGGLGVDIVLDAGVRLYSK 231

  Fly   270 -NNPQAMEELCKYAPYDIVLDCAGQGGQKAAESKYDFRQYITFSSPL------------------ 315
             :.|....:|..: .:||: ...|.||           .::|....|
Human   232 DDEPAVKLQLLPH-KHDII-TLLGVGG-----------HWVTTEENLQLDPPDSHCLFLKGATLA 283

  Fly   316 --------LANIDKQGLGVGALKNVFDLFQTNV 340
                    |:|: :||..:..||:|.:...|.|
Human   284 FLNDEVWNLSNV-QQGKYLCILKDVMEKLSTGV 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17221	NP_608746.1	RTN4I1	52..406	CDD:176210	78/358 (22%)
CRYZL1	NP_665857.2	enoyl_red	31..347	CDD:176179	72/325 (22%)