Protein Alignment Prp40 and prp40

DIOPT Version :10

• Sequence 1: NP_608738.1
• Gene: Prp40 / 33513
• FlyBaseID: FBgn0031492
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_594966.1
• Gene: prp40 / 2543409
• PomBaseID: SPAC4D7.13
• Length: 695
• Species: Schizosaccharomyces pombe
• Alignment Length: 723
• Identity: 186/723 - (25%)
• Similarity: 321/723 - (44%)
• Gaps: 107/723 - (14%)

  Fly    53 STEWTEHKAPDGRPYYYNQNTKQSSWEKPEALMTPAELLHNQCPWKEYRSDTGKVYYHNVATKET 117
            :::|.|.|..|.|.||||..|::|.|||||.||...|...::..||||.:..||.|::||.|:|:
pombe    33 ASDWHEVKTEDSRVYYYNSVTRKSVWEKPEELMNDFEKKLSKLAWKEYATADGKKYWYNVNTRES 97

  Fly   118 CWEPPPEYVDMKAKAKAEEAAAAAKAVAAMTSSSLAGMVPPAALASILPAALPVAPRLPTPEIHS 182
            .|:.|.||   || |..:|.....||:::...|:                  ...|.:.:.:.|.
pombe    98 VWDIPDEY---KA-ALVDEPEQQKKALSSKIKSN------------------DNKPAVQSIQRHG 140

  Fly   183 P--LTPSSNENSSSAMDQAMAATLAAIEVPQQNAKKDDKSESAVVFK----DKREAIE-SFKELL 240
            |  ..|||......:...:..:....|...||..|:..:|..   ::    |..||.| :|.:.|
pombe   141 PDVAAPSSQPAKDQSQQISQGSHKRTINFVQQKDKRQKRSND---YQHENYDTYEAAERAFFKFL 202

  Fly   241 RDRNVPSNANWDQCVKIISKDPRYAAFKNLNERKQTFNAYKTQKIKDEREESRLKAKKAKEDLEQ 305
            ...||..:..|:|.|:.:.....|...|:...||..|:||....:.|:.:..:.:..|.:::..:
pombe   203 DSHNVNPSWTWEQTVRELCDAKGYYVMKDPWHRKCAFDAYILNYLTDQSDAEKNRVTKIRKEFIE 267

  Fly   306 FLMSSDKMNSQMKYFRCEEVFAGTRTWTAV-PEPDRRDIYEDCIFNLAKREKEEARLLKKRNMKV 369
            .|.||||::|...:...:..|:....:.|. .|.:::.::.:....|.:.||:   |.|.|..:.
pombe   268 MLKSSDKIHSYTLWRTVKNEFSSHPAFNATSSETEQQQLFFEYKQKLLEDEKQ---LEKDRRKEA 329

  Fly   370 LGELLESMTSINHA--TTWSEAQVMLLDNVAFKNDVTLLGMDKEDALIVFEEHIRTLEKEEDEER 432
            |.:....:.::|..  |.||.||.....:..:..:..:..:.|.|||:.||:|::.||:|...::
pombe   330 LDDFCSLLRNMNFEPYTRWSVAQAKFDQDPRYTRNSNMKYLSKLDALVAFEDHVKHLEREYILDK 394

  Fly   433 EREKKRMKRQQRKNRDSFLALLDSLHEEGKLTSMSLWVELYPIISADLRFSAMLGQSGSTPLDLF 497
            :::||...|.:|||||:|.|||..|..:.|:|..:.|.||||||..|.|:..:||||||||||||
pombe   395 QKQKKEKHRIERKNRDAFRALLQDLRVQKKITLRTKWKELYPIIKDDPRYLNLLGQSGSTPLDLF 459

  Fly   498 KFYVENLKARFHDEKKIIREILKEKAFVVQAKTSFEDFATVVCED----KRSASLDAGNVKLTYN 558
            ...:.:|:..:.:::.::.:.|:.....|...::..:....:.|.    :.|.::....::...|
pombe   460 WDTIVDLENMYREKRNLVLDCLEVLQISVDDTSNIPEIIARLSEKLKDREESEAVTEDLIEEVVN 524

  Fly   559 SLLEKAEAIEKERMKEEVRRLRKLENEIKN--EWLEANVSVAEPYESAKKLVEHLEAFALYEKEI 621
            .|.:||...:.|..:.:.||:|:..:.:::  ::|:..:|....|:..:.|:..|..||..
pombe   525 RLRDKAIHKKAEEKRADERRIRRKIDNLRSAIKYLKPPISADASYDEIRPLISILPEFAAL---- 585

  Fly   622 GVEKIWEDFVKESEDACSHHHSRSRKSKKNKKHKKRVRSVSRSDIENEHIEVEKSKRR------- 679
                                ||...:.....|:.:|:|       |...:|.:...||
pombe   586 --------------------HSEEHRMAAFDKYIRRLR-------EKRELEKQYQNRRGYYDVGK 623

  Fly   680 -----RSKTRSHSLTSIGSIESEKLLKKKKKRKNKLRGSSCESDVPGIQSPGTQALLQNDSNSH- 738
                 .:..|.||....|.:|....|..|..| |::               .|...:|.:|.||
pombe   624 DESYLANSARPHSGYEDGRLEYSADLASKSNR-NEI---------------NTMQDVQENSISHV 672

  Fly   739 ---SPAKK 743
               .||.|
pombe   673 TATQPAVK 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp40	NP_608738.1	PRP40	54..634	CDD:227435	160/595 (27%)
prp40	NP_594966.1	PRP40	20..683	CDD:227435	186/723 (26%)