Protein Alignment okr and RDH54

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_009629.6
• Gene: RDH54 / 852365
• SGDID: S000000277
• Length: 958
• Species: Saccharomyces cerevisiae
• Alignment Length: 820
• Identity: 264/820 - (32%)
• Similarity: 405/820 - (49%)
• Gaps: 176/820 - (21%)

  Fly     2 RRSLAPSQRGPLRPESRHSFTPPLLKKNKRSCQQELEREQELDR-RRLGALRDASNTSELPLPIR 65
            :.:|:.:...|..|.:..:.|.|..|.:....|..|.:...|:. :|..::...:|.....:| :
Yeast   188 KEALSQNMGNPSPPTTSTTETVPSTKNDGGKYQMPLSQLFSLNTVKRFKSVTKQTNEHMTTVP-K 251

  Fly    66 FTANSEYELAIAKVLARKFKVPMDNYVPDYGGKRVLGVRRCISRRPLHDPMACNALVLFHPPAYT 130
            .:.||:         |:|:                         .|:.|....:..::.:..|..
Yeast   252 TSQNSK---------AKKY-------------------------YPVFDVNKIDNPIVMNKNAAA 282

  Fly   131 EHERMGMDPTKVLVHVVVDPLLSNILRPHQREGVRFMYECVEG---------------------K 174
            |            |.|:|||||...|||||||||:|||:|:.|                     .
Yeast   283 E------------VDVIVDPLLGKFLRPHQREGVKFMYDCLMGLARPTIENPDIDCTTKSLVLEN 335

  Fly   175 RGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGP-----ECKPT-------INKAIVVSPSSLVKN 227
            ..:.:||::||:|||||||..:||:|||:||.|     .|..:       ..|.:||.|.:|:.|
Yeast   336 DSDISGCLLADDMGLGKTLMSITLIWTLIRQTPFASKVSCSQSGIPLTGLCKKILVVCPVTLIGN 400

  Fly   228 WEKEFTKWLH-GRLLCLPMEGGTKENTIR-ALEQFSMTSARLGTPVLLISYETFRIYAEIL--CK 288
            |::||.|||: .|:..|.:......:..: |:..|  ...:....||:|.||.....:|.|  .|
Yeast   401 WKREFGKWLNLSRIGVLTLSSRNSPDMDKMAVRNF--LKVQRTYQVLIIGYEKLLSVSEELEKNK 463

  Fly   289 YEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAV 353
            :.:.|::|||||||||..:.....|..|..:|::||:||||||||.|::::::|:||.:||:.|.
Yeast   464 HLIDMLVCDEGHRLKNGASKILNTLKSLDIRRKLLLTGTPIQNDLNEFFTIIDFINPGILGSFAS 528

  Fly   354 FKRNFESAILRGQNTDS--TEQERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAK 416
            |||.|...|.|.::|.:  .|:..::..|:::|:|.:..:.|:||||.||.||||.|.::::..|
Yeast   529 FKRRFIIPITRARDTANRYNEELLEKGEERSKEMIEITKRFILRRTNAILEKYLPPKTDIILFCK 593

  Fly   417 LTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTLKKICSHPDLI----YEKLTAREKGF 477
            ..:.|:..:.:.|:..::     |..:....::|..||.|||:|:.|.|:    |.|...::...
Yeast   594 PYSQQILAFKDILQGARL-----DFGQLTFSSSLGLITLLKKVCNSPGLVGSDPYYKSHIKDTQS 653

  Fly   478 ENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYG 542
            ::|.:        :.||   |||..:|..:|..||....:|||::||||||||:.|.|.......
Yeast   654 QDSYS--------RSLN---SGKLKVLMTLLEGIRKGTKEKVVVVSNYTQTLDIIENLMNMAGMS 707

  Fly   543 FVRLDGTMSIKKRSKVVDRFN-DPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQA 606
            ..||||::..|:|..:|..|| :|.  .|.|:||:|:||.||||:||:||.:||.||||:.|.||
Yeast   708 HCRLDGSIPAKQRDSIVTSFNRNPA--IFGFLLSAKSGGVGLNLVGASRLILFDNDWNPSVDLQA 770

  Fly   607 MARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEKH------FTRDDLK 665
            |:|:.||||||||:|||||.:|.|:|||||||..|.|||...:.::|...|.      |.::|||
Yeast   771 MSRIHRDGQKKPCFIYRLVTTGCIDEKILQRQLMKNSLSQKFLGDSEMRNKESSNDDLFNKEDLK 835

  Fly   666 DLFTFDANILSDTHDKLKCKRCVQNIQMKPPPEDTDCTSHLSQWYHCSNNRGLPDNILAQAWMDC 730
            |||:...:..|:|||.:                                               |
Yeast   836 DLFSVHTDTKSNTHDLI-----------------------------------------------C 853

  Fly   731 KCVSFVFHHRSQAQEIVPSAEEEATDQPEEKPESRKRSST 770
            .|...       .:||    |...|:|.:...|.||||:|
Yeast   854 SCDGL-------GEEI----EYPETNQQQNTVELRKRSTT 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	4/49 (8%)
		HepA	<156..650	CDD:440319	211/537 (39%)
		DEXHc_RAD54A	156..396	CDD:350825	100/278 (36%)
RDH54	NP_009629.6	DUF2439	108..>158	CDD:463065
		DEXHc_RAD54	296..573	CDD:350762	100/278 (36%)
		SF2_C_SNF	663..789	CDD:350180	67/127 (53%)