Protein Alignment okr and CHD6

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_016883588.1
• Gene: CHD6 / 84181
• HGNCID: 19057
• Length: 2716
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 181/667 - (27%)
• Similarity: 297/667 - (44%)
• Gaps: 100/667 - (14%)

  Fly   153 SNILRPHQREGVRFM----YECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTI 213
            ||.||.:|.||:.::    |        |...||:|||||||||:|.:|.:..:..:|..
Human   459 SNQLREYQLEGMNWLLFNWY--------NRKNCILADEMGLGKTIQSITFLSEIFLRGIH----- 510

  Fly   214 NKAIVVSPSSLVKNWEKEFTKW-------LHGRLLCLPMEGGTKENTIRALEQFSMT--SARLGT 269
            ...::::|.|.:.|||:||..|       .||..:...|           ::|:.|.  .|: |.
Human   511 GPFLIIAPLSTITNWEREFRTWTEMNAIVYHGSQISRQM-----------IQQYEMVYRDAQ-GN 563

  Fly   270 P--------VLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSG 326
            |        |::.::|........|.|.....||.||.|||||.:....:.|..:..:.:|||:|
Human   564 PLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTG 628

  Fly   327 TPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQ 391
            ||:||.:.|.:||:||:.|....:...|...|...        .||       |:.::|..::..
Human   629 TPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDL--------KTE-------EQVKKLQSILKP 678

  Fly   392 CIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTL 456
            .::||....:.|.|..|.|.:|..:||.||.:.|...|:.: ........|:......:..:..|
Human   679 MMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKN-FSFLTKGANQHNMPNLINTMMEL 742

  Fly   457 KKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNP--ELSGKFMLLDFMLAAIRAEGNDKV 519
            :|.|:||.||.   .|.||..|:.:.....:.....|..  :.:||.:|:|.:|..:.| |..||
Human   743 RKCCNHPYLIN---GAEEKILEDFRKTHSPDAPDFQLQAMIQAAGKLVLIDKLLPKLIA-GGHKV 803

  Fly   520 VLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLN 584
            ::.|...:.||:.|....:|:|.:.|:||.:....|...:|||..|:||.|:|:|.::|||.|:|
Human   804 LIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGIN 868

  Fly   585 LIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTII 649
            |..|:...:||.||||.||.||.||..|.||.|...:|||:...|.|.::..:.:.|..|...::
Human   869 LTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVL 933

  Fly   650 DN-----NESAEKHFTRDDLKDLFTFDA-NILSDTHDKLK--CKRCVQNIQMKPP-----PEDTD 701
            .:     ..:..:..::.:::||....| ..|.|..|:..  |:..:..|..:..     ..:..
Human   934 QDINRKGGTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGK 998

  Fly   702 CTSHLSQWYHCSNNR---GLPDNILAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEEKPE 763
            .::.....:..|.||   .|.|....|.|             ::..|:...|:.|......::|.
Human   999 GSTFAKASFVASGNRTDISLDDPNFWQKW-------------AKIAELDTEAKNEKESLVIDRPR 1050

  Fly   764 SRKRSSTPASDDSADED 780
            .||::.   ..:|.:||
Human  1051 VRKQTK---HYNSFEED 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	155/516 (30%)
		DEXHc_RAD54A	156..396	CDD:350825	71/260 (27%)
CHD6	XP_016883588.1	PTZ00449	<105..374	CDD:185628
		CD1_tandem_CHD5-9_like	289..354	CDD:349315
		CD2_tandem_CHD5-9_like	373..431	CDD:349310
		PLN03142	461..>986	CDD:215601	163/569 (29%)
		DEXHc_CHD6	462..683	CDD:350816	71/260 (27%)
		PHA03247	<2320..2694	CDD:223021
		BRK	2403..2438	CDD:470653