Protein Alignment okr and Rad54l2

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_109655.2
• Gene: Rad54l2 / 81000
• MGIID: 1933196
• Length: 1467
• Species: Mus musculus
• Alignment Length: 978
• Identity: 262/978 - (26%)
• Similarity: 420/978 - (42%)
• Gaps: 294/978 - (30%)

  Fly    15 PESRHSFTPPLLKKN--------------KRSCQQELEREQELDRRR-----------LGALRD- 53
            |:.:.:..|..:::|              |.:.|:||||.:.|:::|           |..|.:
Mouse    98 PKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKEYAAPIPTVPLEFLPEE 162

  Fly    54 ----ASNTSELP--------LPIRFTANSE---------YELAIAK-----VLARKFKVPMDNYV 92
                ||:..:||        :.:..::.||         .||:..:     ::.....|..::..
Mouse   163 IVLRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEEDEE 227

  Fly    93 PDYGGKRVLGVRRCISRRPLHDPMACNALVLFHPPAYTEHERMGMDPTKVLVHVVVDPLLSNILR 157
            .:.||..   |...:::   ||.:....:.|.|||   |.|           :|.:.|.|:..::
Mouse   228 EEKGGTH---VNDALNQ---HDALGRVLVNLNHPP---EEE-----------NVFLAPQLARAVK 272

  Fly   158 PHQREGVRFMYE-CVEG----KRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAI 217
            |||..|:||:|: .||.    |..:..|||:|..||||||||.::.:..|.|..|     ....:
Mouse   273 PHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTP-----AKTVL 332

  Fly   218 VVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRAL-------EQFSMTSARLGTP----- 270
            .:.|.:.::||..||..||... ..||.:...:|...|..       |..::.|....|.
Mouse   333 AIVPVNTLQNWLAEFNMWLPAP-EALPADSKPEEVQPRFFKVHILNDEHKTVASRAKVTADWVSE 396

  Fly   271 --VLLISYETFRI--------------------------------------YAEILCKYEVGMVI 295
              |||:.||.:|:                                      :.:.||:....:||
Mouse   397 GGVLLMGYEMYRLLTLKKSLATSRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVI 461

  Fly   296 CDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFES 360
            ||||||:||....|.|||..::::|||:|:|.|:||:|.||:.:|:||.|:.|||...|...||.
Mouse   462 CDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFER 526

  Fly   361 AILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELY 425
            .||.||..|||.|:.:....::..|..|::..:.||.:.:|..:||.|.|.||..:|:.||.:||
Mouse   527 PILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSQIQRDLY 591

  Fly   426 TNFLKSDQVRRSLADCNEKA--SLTALADITTLKKICSHPDLIYEKLTAREKGFENSQNV----- 483
            |.|:  |:.|    ||....  .|..|.......||.:|||::||.|  :::...|.|::
Mouse   592 TQFM--DRFR----DCGTSGWLGLNPLKAFCVCCKIWNHPDVLYEAL--QKENLANEQDLDVEEL 648

  Fly   484 ----------------------LPS-------------------------------------NYK 489
                                  |||                                     ||:
Mouse   649 GSAGTSARCPPHGTKVKGEDSALPSSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKELLTNYQ 713

  Fly   490 PKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARK---------------- 538
            ...|  |.|.|.:|| |.|.....:..||:::.|....||.|.|:...|
Mouse   714 TGVL--ENSPKMVLL-FHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRDMPCLPGAEGQGTQK 775

  Fly   539 --RKYGFVRLDGTMSIKKRSKVVDRFNDPES-DSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNP 600
              |...:.||||:....:|.:::::||||.: .::||:||::||..|:|||||||:.:||..|||
Mouse   776 WVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNP 840

  Fly   601 ANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEKHFTRDDLK 665
            .:|.||:.||:|.||||||:||||||..::|:||..||..|:.:|..::| :.:...:|||.:::
Mouse   841 CHDAQAVCRVYRYGQKKPCHIYRLVADYTLEKKIYDRQISKQGMSDRVVD-DLNPMLNFTRKEVE 904

  Fly   666 DLFTFDANILSDTHDKLKCKRCVQNIQMKPPPEDTDCTSHLSQWYHCSNNRGLPDNILAQAWMDC 730
            :|..|                    ::.:|.|:.:            .:.:|:.:::|..|
Mouse   905 NLLHF--------------------VEKEPAPQTS------------LDIKGIKESVLQLA---- 933

  Fly   731 KCVSF-------VFHHRS----QAQEIVPSAEEEATDQPEEKPESRKRSST-----------PAS 773
             |:.:       .|.|.|    :....:..||::|.   ::..|..||:|.           |||
Mouse   934 -CLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAA---KKSYEEDKRTSVPYTRPSYAQYYPAS 994

  Fly   774 DDS 776
            |.|
Mouse   995 DQS 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	7/54 (13%)
		HepA	<156..650	CDD:440319	199/635 (31%)
		DEXHc_RAD54A	156..396	CDD:350825	92/296 (31%)
Rad54l2	NP_109655.2	HepA	110..890	CDD:440319	233/816 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..236		7/52 (13%)
		DEXHc_ARIP4	271..547	CDD:350827	90/281 (32%)
		DEAH box	463..466		2/2 (100%)
		LXXLL motif 1	551..555		1/3 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	650..671		0/20 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1027..1046
		PHA03247	<1112..1445	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1121..1171
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1185..1213
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1260..1282
		LXXLL motif 2	1329..1333
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1445..1467