Protein Alignment okr and smarca4a

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_853634.1
• Gene: smarca4a / 353295
• ZFINID: ZDB-GENE-030605-1
• Length: 1627
• Species: Danio rerio
• Alignment Length: 743
• Identity: 199/743 - (26%)
• Similarity: 321/743 - (43%)
• Gaps: 157/743 - (21%)

  Fly   136 GMDPTKVLVHVVVDP-------LLSNILRPHQREGVRFMYECVEGKRGNFNGCIMADEMGLGKTL 193
            |:.....:.|.|.:.       |::..|:.:|.:|:.::   |.....|.|| |:|||||||||:
Zfish   739 GLQSYYAVAHAVTEKVEKQSSLLVNGQLKQYQIKGLEWL---VSLYNNNLNG-ILADEMGLGKTI 799

  Fly   194 QCVTLVWTLLRQGPECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALE 258
            |.:.|:..|:    |.|......:::.|.|.:.||..||.||              ..:.::...
Zfish   800 QTIALITYLM----EFKRLNGPFLIIVPLSTLSNWVYEFDKW--------------APSVVKVSY 846

  Fly   259 QFSMTSARLGTP--------VLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSD-------NL 308
            :.|..:.|...|        ||:.:||......::|.|.....:|.|||||:||..       |.
Zfish   847 KGSPAARRAFLPILRSGKFNVLVTTYEYIIKDKQVLAKLRWKYMIVDEGHRMKNHHCKLTQVLNT 911

  Fly   309 TYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAI-LRGQNTDSTE 372
            .|.|      .|||||:|||:||.|.|.::|:||:.|.:..:.:.|::.|.:.. :.|:..|..|
Zfish   912 HYLA------PRRVLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNE 970

  Fly   373 QERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRS 437
            :|....|.:..:::   ...::||..:.:...||.|.|.||...::|:|..||.:......:
Zfish   971 EETILIIRRLHKVL---RPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVL--- 1029

  Fly   438 LADCNEK------ASLTALADITTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNPE 496
            |.|.:||      .:.|.:..|..|:|||:|| .:::.:   |:.|...........:..||. .
Zfish  1030 LTDGSEKDKKGKGGTKTLMNTIMQLRKICNHP-YMFQHI---EESFSEHLGFTGGIVQGSDLY-R 1089

  Fly   497 LSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDR 561
            .||||.|||.:|..:||. |.||:|....|..:.:.|.....|.:.::|||||...:.|..::..
Zfish  1090 ASGKFELLDRILPKLRAT-NHKVLLFCQMTTLMTIMEDYFAYRNFKYLRLDGTTKAEDRGMLLKN 1153

  Fly   562 FNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVA 626
            ||||....|:|:||::|||.||||..|:.:.:||.||||..|.||..|..|.||:....:.||..
Zfish  1154 FNDPSHQYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCT 1218

  Fly   627 SGSIEEKILQRQTHKKSLSSTII-----DNNESAE----------KHFTRDDLKDLFTFDANI-- 674
            ..|:|||||....:|.::...:|     |...|:.          :|..:|:.:|....|..:
Zfish  1219 VNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDETVNQ 1283

  Fly   675 -LSDTHDKL---------KCKRCVQNIQMKPPPEDTDCTSHLSQW----------YHCSN----- 714
             ::.:.::.         :.:...:|.:.:|...:.|   .|..|          ..|..
Zfish  1284 MIARSEEEFDHFMRMDLDRRREEARNPKRRPRLMEED---ELPTWIMKDDAEVERLTCEEEEEKM 1345

  Fly   715 -NRG--------LPDNILAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEE----KPESRK 766
             .||        ..|::..:.|:                   .:.||...|:.||    |..:||
Zfish  1346 FGRGSRQRKEVDYSDSLTEKQWL-------------------KAIEEGTLDEIEEEVRHKKTTRK 1391

  Fly   767 RS----------STPASDD-SADEDFRG 783
            |.          :||:|.. |.|:|..|
Zfish  1392 RKRDRDLDLPGPATPSSSGRSRDKDDDG 1419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	163/520 (31%)
		DEXHc_RAD54A	156..396	CDD:350825	73/255 (29%)
smarca4a	NP_853634.1	Med15	<65..>360	CDD:312941
		QLQ	198..231	CDD:462622
		Smc	<382..>624	CDD:440809
		HSA	478..550	CDD:214727
		BRK	629..672	CDD:462196
		DEXHc_SMARCA4	743..993	CDD:350820	78/280 (28%)
		PLN03142	762..>1244	CDD:215601	163/521 (31%)
		SnAC	1301..1368	CDD:464219	9/69 (13%)
		Bromo_SNF2L2	1440..1545	CDD:99947