Protein Alignment okr and Smarca4

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_011240739.1
• Gene: Smarca4 / 20586
• MGIID: 88192
• Length: 1670
• Species: Mus musculus
• Alignment Length: 756
• Identity: 204/756 - (26%)
• Similarity: 332/756 - (43%)
• Gaps: 147/756 - (19%)

  Fly    34 QQELEREQELDRRRLGALRDASNTSELPLPIRFTANSEYELAIAKVLARKFKVPMDNYVPDYGGK 98
            ::|.|.|:|..:.............::|.|     :|:   .:::|.||..   ::|...|...:
Mouse   684 EEEEEEEEEQPQPAQPPTLPVEEKKKIPDP-----DSD---DVSEVDARHI---IENAKQDVDDE 737

  Fly    99 RVLGVRRCISRRPLHDPMACNALVLFHPPAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQREG 163
              .||.:.::|          .|..::..|:...||  :|....|       :::.:|:.:|.:|
Mouse   738 --YGVSQALAR----------GLQSYYAVAHAVTER--VDKQSAL-------MVNGVLKQYQIKG 781

  Fly   164 VRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLVKNW 228
            :.::   |.....|.|| |:|||||||||:|.:.|:..|:    |.|......:::.|.|.:.||
Mouse   782 LEWL---VSLYNNNLNG-ILADEMGLGKTIQTIALITYLM----EHKRINGPFLIIVPLSTLSNW 838

  Fly   229 EKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTP--------VLLISYETF----RI 281
            ..||.||              ..:.::...:.|..:.|...|        |||.:||..    .|
Mouse   839 AYEFDKW--------------APSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHI 889

  Fly   282 YAEILCKYEVGMVICDEGHRLKNSD-------NLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSL 339
            .|:|..||    :|.|||||:||..       |..|.|      .||:||:|||:||.|.|.::|
Mouse   890 LAKIRWKY----MIVDEGHRMKNHHCKLTQVLNTHYVA------PRRLLLTGTPLQNKLPELWAL 944

  Fly   340 VNFVNPEMLGTAAVFKRNFESAI-LRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQILTK 403
            :||:.|.:..:.:.|::.|.:.. :.|:..|..|:|....|.:..:::   ...::||..:.:..
Mouse   945 LNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVL---RPFLLRRLKKEVEA 1006

  Fly   404 YLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEK------ASLTALADITTLKKICSH 462
            .||.|.|.||...::|:|..||.:......:   |.|.:||      .:.|.:..|..|:|||:|
Mouse  1007 QLPEKVEYVIKCDMSALQRVLYRHMQAKGVL---LTDGSEKDKKGKGGTKTLMNTIMQLRKICNH 1068

  Fly   463 PDLIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQ 527
            | .:::.:   |:.|...........:..||. ..||||.|||.:|..:||. |.||:|....|.
Mouse  1069 P-YMFQHI---EESFSEHLGFTGGIVQGLDLY-RASGKFELLDRILPKLRAT-NHKVLLFCQMTS 1127

  Fly   528 TLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLF 592
            .:.:.|.....|.:.::|||||...:.|..::..||:|.|:.|:|:||::|||.||||..|:.:.
Mouse  1128 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVI 1192

  Fly   593 MFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEK 657
            :||.||||..|.||..|..|.||:....:.||....|:|||||....:|.::...:|......:|
Mouse  1193 IFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQK 1257

  Fly   658 HFTRDDLKDLFTFDANILSDTHDKLKCKRCVQNIQMKPPPEDTDCTSHLSQWYHCSNNRGLPDNI 722
                              |.:|::....:.:..      .|:.|      :..|||...|
Mouse  1258 ------------------SSSHERRAFLQAILE------HEEQD------ESRHCSTGSG----- 1287

  Fly   723 LAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEEKPE 763
                     ..||. |.......:.|..||....:.:|.|:
Mouse  1288 ---------SASFA-HTAPPPAGVNPDLEEPPLKEEDEVPD 1318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	9/49 (18%)
		HepA	<156..650	CDD:440319	165/519 (32%)
		DEXHc_RAD54A	156..396	CDD:350825	76/259 (29%)
Smarca4	XP_011240739.1	Med15	62..>237	CDD:312941
		QLQ	191..225	CDD:462622
		Smc	<384..>590	CDD:440809
		HSA	480..552	CDD:214727
		BRK	632..676	CDD:197800
		DEXHc_SMARCA4	751..1001	CDD:350820	83/293 (28%)
		PLN03142	770..>1252	CDD:215601	166/525 (32%)
		SnAC	1342..1409	CDD:464219
		Bromo_SNF2L2	1481..1587	CDD:99947