Protein Alignment okr and chd-7

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_491426.2
• Gene: chd-7 / 172079
• WormBaseID: WBGene00007053
• Length: 2967
• Species: Caenorhabditis elegans
• Alignment Length: 861
• Identity: 223/861 - (25%)
• Similarity: 368/861 - (42%)
• Gaps: 180/861 - (20%)

  Fly     3 RSLAPSQRGPLRPESRHSFTPPLLKKNKRS---CQQELERE-QELDRRRLGALRDASNTSELPLP 63
            :|...|:...:..|....|   |:|...||   |:.:...| .|:|:|
 Worm  1042 KSKTESETNEIEEEEVEQF---LIKWKGRSYVHCEWKTAAELLEIDKR----------------- 1086

  Fly    64 IRFTANSEYELAIAKVLARKFKV-PMDNYV---PDYGGKRVLGVRRCISRRPLHDPMACNALVLF 124
                       ..||:  ::||| .|.:|:   .|:....|: |.|.:......|.... .|:.:
 Worm  1087 -----------VEAKI--KRFKVKKMSSYIEDDEDFNSDFVI-VDRVVDLITEDDGQEF-VLIKW 1136

  Fly   125 HPPAYTE-----------------HERMGMDPTKVLVHVVVDP------------LLSNILRPHQ 160
            ....|.|                 .||..:||.|:......:|            ...|.||.:|
 Worm  1137 KSLGYEEVTWEPIEMIPADKVELWRERQVIDPAKIREKQRPEPEEWKKMSTSKVWKNGNSLREYQ 1201

  Fly   161 REGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLV 225
            .|||.::..|..    |...||:|||||||||:|.:|.:..:...|..     ...:||.|.|.:
 Worm  1202 FEGVDWLLYCYY----NAQNCILADEMGLGKTVQTITFLSRIYDYGIH-----GPFLVVVPLSTI 1257

  Fly   226 KNWEKEFTKWLHGRLLCLPMEGGTKENTI---------RALEQFSMTSAR------------LGT 269
            :||.:||..|             |..|.|         ..|:|:.:...:            :..
 Worm  1258 QNWVREFETW-------------TDMNAIVYHGSAYAREVLQQYEVFYDKRHCGAKNWKKNFVKI 1309

  Fly   270 PVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSD-NLTYQALMGLKTKRRVLLSGTPIQNDL 333
            ..|:.::||.....|.|.|....:.:.||.|||||.: .|....|:..:.:.||||:|||:||::
 Worm  1310 DALITTFETVVSDVEFLKKIPWRVCVIDEAHRLKNRNCKLLVNGLLAFRMEHRVLLTGTPLQNNI 1374

  Fly   334 TEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTN 398
            .|.:||:||::|:....:|.|...|.|.     .||.       .::|.||::   ...::||..
 Worm  1375 DELFSLLNFLHPQQFDNSATFLEQFGSC-----QTDD-------QVQKLQEIL---KPMMLRRLK 1424

  Fly   399 QILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADI-TTLKKICSH 462
            :.:.|.|..|.|.:|..:|:.:|.:.|...|:     |:.:...:..|..:|.:: ..|:|.|:|
 Worm  1425 EDVEKSLGPKEETIIEVQLSDMQKKFYRAILE-----RNFSHLCKGTSAPSLMNVMMELRKCCNH 1484

  Fly   463 PDLIYEKLTAREKGFENSQNVLPSNYKPKDLNP----ELSGKFMLLDFMLAAIRAEGNDKVVLIS 523
            |.||    ...|:...|...:...::..:.|..    :.|||.:|::.:|..:|.:|: ||::.|
 Worm  1485 PFLI----NGAEEAIMNDFRLAHPDWDEETLAHKALIQASGKVVLIEKLLPKLRKDGH-KVLIFS 1544

  Fly   524 NYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGA 588
            ...:.|||.|:......|.|.|:||.:....|...:|||:...||.|:|:|.::|||.|:||..|
 Worm  1545 QMVKVLDLLEEFLISMSYPFERIDGNVRGDLRQAAIDRFSKENSDRFVFLLCTRAGGLGINLTAA 1609

  Fly   589 NRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNE 653
            :.:.:||.||||.||.||.||..|.||||...:|||:.|.:.|.::..:.:.|..|...::.:..
 Worm  1610 DTVIIFDSDWNPQNDLQAQARCHRIGQKKLVKVYRLITSNTYEREMFDKASLKLGLDKAVLQSTT 1674

  Fly   654 SAEKHFT---RDDLKDLFTFDA--NILSDTHDKLK---------CKRCVQNIQMKPPPEDTDCTS 704
            :.:...|   :.|:::|....|  :|:.:.::..|         .:|..|.|.::...:.   :.
 Worm  1675 ALKAEGTALSKKDVEELLKKGAYGSIMDEENESSKFNEEDIETILQRRTQTITLEAGQKG---SL 1736

  Fly   705 HLSQWYHCSNNRGLPDNILAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEEK----PESR 765
            .....::.|:|:|  |:|      |.....|......:||..|    |:||..|:.:    .|.|
 Worm  1737 FAKATFNSSHNKG--DDI------DIDDPEFWTKWAEKAQVDV----EKATATPDGRELIIEEPR 1789

  Fly   766 KRSST-PASDDSADED 780
            ||:.. ..:.|..|.|
 Worm  1790 KRTKRFEENKDEGDSD 1805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	13/53 (25%)
		HepA	<156..650	CDD:440319	158/520 (30%)
		DEXHc_RAD54A	156..396	CDD:350825	75/261 (29%)
chd-7	NP_491426.2	Atrophin-1	<387..>666	CDD:460830
		PRK12323	<582..732	CDD:481241
		CD1_tandem_CHD5-9_like	979..1095	CDD:349315	15/85 (18%)
		CD2_tandem	1112..1162	CDD:349306	7/51 (14%)
		PLN03142	1197..>1803	CDD:215601	186/667 (28%)
		SANT	2073..2133	CDD:197842
		BRK	2672..2716	CDD:197800