Protein Alignment okr and kis

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_061512916.1
• Gene: kis / 1277495
• VectorBaseID: AGAMI1_002666
• Length: 6890
• Species: Anopheles gambiae
• Alignment Length: 681
• Identity: 196/681 - (28%)
• Similarity: 321/681 - (47%)
• Gaps: 121/681 - (17%)

  Fly   154 NILRPHQREGVRFM-YECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLR---QGPECKPTIN 214
            |.|||:|.||:.:: |...:|     |.||:|||||||||:|.:|.|.::..   :||
Mosquito  2662 NKLRPYQLEGLNWLRYSWYKG-----NNCILADEMGLGKTIQSLTFVNSVYEYGIRGP------- 2714

  Fly   215 KAIVVSPSSLVKNWEKEFTKW-------LHG----RLLCLPMEGGTKENT---IRALEQFSMTSA 265
             .:|::|.|.:.||::||..|       .||    |.:....|...:..|   ||.:.:|:
Mosquito  2715 -FLVIAPLSTIPNWQREFEGWTEMNVIVYHGSATSRQMIQDYEVHYRTETGKLIRDITKFN---- 2774

  Fly   266 RLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQ 330
                 ||:.::|......:.|..:.....:.||.|||||.:....:.|..|..:.||||||||:|
Mosquito  2775 -----VLITTFEMIVTDYQDLKNFTWRACVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQ 2834

  Fly   331 NDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIR 395
            |::.|.:||:||:.|.....:..|.|.|.|.        .||.|       ..:|..|:...::|
Mosquito  2835 NNVNELFSLLNFLEPSQFACSEEFLREFGSL--------KTESE-------VLKLQALLKPMMLR 2884

  Fly   396 RTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALAD-ITTLKKI 459
            |....:.|.|..|.|.::..:||.||.:.|...|  :|....|......|::..|.: :..|:|.
Mosquito  2885 RLKDDVEKSLAPKEETIVEVELTNIQKKYYRGIL--EQNFSFLMKGTTSANIPNLMNTMMELRKC 2947

  Fly   460 CSHPDLI--------YEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGN 516
            |.||.|:        |:   .|::..|:::    |.||...::   |||.:|:|.:|..:||.|:
Mosquito  2948 CIHPYLLNGAEDQIQYD---YRQQHGEDAE----SYYKNLIVS---SGKMVLIDKLLPKLRANGH 3002

  Fly   517 DKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGC 581
             :|::.|...:.||:.|.....:||.|.|:||.:....|...:||::.|:||.|:|:|.:||||.
Mosquito  3003 -RVLIFSQMVRCLDILEDYLMYKKYPFERIDGRIRGNLRQAAIDRYSKPDSDRFVFLLCTKAGGL 3066

  Fly   582 GLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSS 646
            |:||..|:.:.::|.||||.||.||.||..|.||:|...||||:...:.|.::..:.:.|..|..
Mosquito  3067 GINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQQKMVKIYRLLCRNTYEREMFDKASLKLGLDK 3131

  Fly   647 TII------DNNESAEKHFTRDDLKDLF---TFDANILSDTHDKLKCKRCVQNIQMKPPP----E 698
            .::      .|.:..::..::.:::||.   .:.|.:..|..||. |:..:.:|.::...    |
Mosquito  3132 AVLQSMNTGQNKDGTQRQLSKKEIEDLLKKGAYGAVMDDDAGDKF-CEEDIDSILLRRTQVITME 3195

  Fly   699 DTDCTSHLSQWYHCSNNR---GLPDNILAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEE 760
            ....::.....:..|.||   .:.|......|             ::..||.|:|.|:  |:.|:
Mosquito  3196 SEKGSTFSKASFAASANRSDINIDDPDFWNKW-------------AKKAEIDPTACEK--DETED 3245

  Fly   761 K--PESRKRSS----------TPASDDSADE 779
            .  .|.|:|:.          ...||:|:.|
Mosquito  3246 LVIAEPRRRTQIKRYGHDDGVMDISDESSGE 3276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	166/526 (32%)
		DEXHc_RAD54A	156..396	CDD:350825	79/257 (31%)
kis	XP_061512916.1	None