Protein Alignment okr and chd2

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_002933353.2
• Gene: chd2 / 100497210
• XenbaseID: XB-GENE-950755
• Length: 1809
• Species: Xenopus tropicalis
• Alignment Length: 836
• Identity: 222/836 - (26%)
• Similarity: 373/836 - (44%)
• Gaps: 176/836 - (21%)

  Fly    32 SCQQELEREQELDRR-----RLGAL---RDASNTSELPLPIRFTANSEYELAIAK---------- 78
            ||||||  ..||:::     |:.|:   :.:|..|:.|:..|.|::|.....:.|
 Frog   367 SCQQEL--ASELNKQYQIVERVIAVKTSKSSSGHSDFPVHSRKTSSSNEPEYLCKWMGLPYSECS 429

  Fly    79 -----VLARKFKVPMDNYVPDYGGKRVLGVRRC--ISRRPLHDPMACNALVLFHPPAYTEHERMG 136
                 ::.:||:..:|:: ......:...|:.|  :.:||       ..:.|...|:|...|  |
 Frog   430 WEDGALVGKKFQHCIDSF-NCRNNSKTTPVKDCKVLRQRP-------RFVTLKKQPSYIGGE--G 484

  Fly   137 MDPTKVLVHVVVDPLLSNILRPHQREGVRFMYE--CVEGKRGNFNGCIMADEMGLGKTLQCVTLV 199
            ::                 ||.:|.||:.::..  |..      |..|:|||||||||:|.::.:
 Frog   485 LE-----------------LRDYQLEGLNWLAHSWCKN------NSVILADEMGLGKTIQTISFL 526

  Fly   200 WTL----LRQGPECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQF 260
            ..|    |..||        .::|.|.|.:.:|::||..|.....:.:.:......||||..|..
 Frog   527 SYLFHLHLLYGP--------FLLVVPLSTLTSWQREFEVWAPDINVVVYIGDLGSRNTIREYEWV 583

  Fly   261 SMTSARLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLS 325
            ...|.::....||.:||.......:|.......:..||.|||||.|:|.|:.|:..|:..|:|::
 Frog   584 HQQSKKMKFNALLTTYEILLKDKAVLSSINWAFLGVDEAHRLKNDDSLLYKTLIEFKSNARLLIT 648

  Fly   326 GTPIQNDLTEYYSLVNFVNPEMLGTAAVFK--RNFESAILRGQNTDSTEQERQRAIEKTQELIGL 388
            |||:||.|.|.:||::|:.||.      |:  .:||..  .|:..|:..|...:.:|
 Frog   649 GTPLQNSLKELWSLLHFIMPEK------FECWEDFEDQ--HGKGRDNGYQSLHKVLE-------- 697

  Fly   389 VDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADI 453
              ..::||..:.:.|.||.|.|.::..::..:|.:.|...|..:.  ::|:.....::...|..:
 Frog   698 --PFLLRRVKKDVEKSLPAKVEQILRVEMCVMQKQYYRWILTRNY--KALSKGTRGSTSGFLNIV 758

  Fly   454 TTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDK 518
            ..|||.|:|..||..:.|.:|...::.|:::.|           |||.:|||.:|..:|..|| :
 Frog   759 MELKKCCNHCFLIKPEETEKESRLDSLQSLIRS-----------SGKLVLLDKLLTRLRERGN-R 811

  Fly   519 VVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGL 583
            |::.|...:.||:..:....:.|.|.||||::..:.|.:.:|.||...|:.|.|:||::|||.|:
 Frog   812 VLIFSQMVRMLDILAEYLAIKHYPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGI 876

  Fly   584 NLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSL---- 644
            ||..|:.:.:||.||||.||.||.||..|.||||...|||||..|::||.|::|...|..|
 Frog   877 NLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTRGTVEEDIIERAKKKMVLDHLV 941

  Fly   645 -------SSTIIDNNESAE--KHFTRDDLKDLFTFD-ANILSDTHDKLKCKRCVQNIQMKPPPED 699
                   ..|::|||..:.  ..|.:|:|..:..|. |::..:|..:          :::|...|
 Frog   942 IQRMDTTGRTVLDNNSGSSNCNPFNKDELAAILKFGAADLFKETEGE----------ELEPQEMD 996

  Fly   700 TDCTSHLSQWYHCSNNRGLPDNILAQAWMDCKCVSF---------VFHHRSQAQEIVP-----SA 750
            .|....|::......:....|.:|:|    .|..:|         |.....:..:|:|     ..
 Frog   997 IDEILRLAETRENEPSSSATDELLSQ----FKVANFATMEEEPEMVLKREQEWDDIIPEGQRKKV 1057

  Fly   751 EEEATDQP--------------------------EEKPESRKRSSTPASDDSADED 780
            ||||..:.                          |.|.::::.|.:.:..|.:|:|
 Frog  1058 EEEARQKELQEIYMLPRIRSLNKKPQANDSESDLESKQKAQRSSGSESDSDDSDDD 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	9/66 (14%)
		HepA	<156..650	CDD:440319	162/512 (32%)
		DEXHc_RAD54A	156..396	CDD:350825	73/247 (30%)
chd2	XP_002933353.2	CD1_tandem_CHD1-2_like	264..346	CDD:349313
		CD2_tandem_CHD1-2_like	379..450	CDD:349308	12/71 (17%)
		DEXHc_CHD2	467..703	CDD:350812	80/293 (27%)
		PLN03142	471..>1005	CDD:215601	180/608 (30%)
		CDH1_2_SANT_HL1	1132..1220	CDD:465731
		DUF4208	1466..1548	CDD:464035