Protein Alignment okr and ercc6l

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_002936822.1
• Gene: ercc6l / 100135235
• XenbaseID: XB-GENE-988849
• Length: 1361
• Species: Xenopus tropicalis
• Alignment Length: 701
• Identity: 198/701 - (28%)
• Similarity: 344/701 - (49%)
• Gaps: 106/701 - (15%)

  Fly   152 LSNILRPHQREGVRFMYECV-EGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINK 215
            |.|.|..||:|||.|:|... :|::|.    |:||:||||||:|.:..:     .|......|..
 Frog   103 LYNKLFEHQKEGVAFLYSLYRDGRKGG----ILADDMGLGKTIQVIGFL-----SGMFDSELIKY 158

  Fly   216 AIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTPVLLISYETFR 280
            .::|.|::|:.||.|||.||..| |......|.:|:...|.||:....|.     :::.:|:...
 Frog   159 VLLVMPTTLISNWVKEFQKWTPG-LRVAEFHGTSKKERTRNLEKIQRMSG-----IIITTYQMLI 217

  Fly   281 IYAEILCKY-----EVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLV 340
            ...:.|..|     |...:|.||.|::|.|...|.::...:..|.|:||:||||||:|.|.::|.
 Frog   218 NNWQQLATYNGREFEWDYIILDEAHKIKTSSTKTAKSCHSIPAKNRILLTGTPIQNNLREMWALY 282

  Fly   341 NFV-NPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRT-NQILTK 403
            :|. ...:|||:..||..:|:.|.|.:..|:|..|:...::.::.|:.::....:||| :.:..|
 Frog   283 DFACQGTLLGTSKTFKMEYENPITRAREKDATPGEKALGLKISENLMKIIQPYFLRRTKSDVQNK 347

  Fly   404 -----------------YLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALA 451
                             .|..|.:.::...|:.||.::|..|:..||::..|     ..:.:.||
 Frog   348 KTERTRAQDTSQGPSMPSLTRKNDFIVWVYLSTIQEDVYRKFISLDQIKELL-----MTTRSPLA 407

  Fly   452 DITTLKKICSHPDLIYEKLTAR---EKGFE----------NSQNVLPSNYKPKDLNPELSGKFML 503
            ::..|||:|.||.|    |:||   :.|.|          :.:.|...::...::..|.|||.:|
 Frog   408 ELNILKKLCDHPRL----LSARACIQLGLEGDDYHSNEEGDHELVTKFDHLSDEILIEESGKLLL 468

  Fly   504 LDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESD 568
            |..:|..::.||: :.::.|...:.||:.:::.:.:.:..:|:|||:::.:|.|.:..|....:.
 Frog   469 LIDLLHKLKEEGH-RTLVFSQSRKMLDMIDRILQNKNFKVMRIDGTVALPEREKRISIFQSNNNY 532

  Fly   569 SFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEK 633
            |.| :|:::.||.||.|..|:|:.:|||.||||.|.||:.|.:|.||::...||||:..|::|||
 Frog   533 SVL-LLTTQVGGVGLTLTAADRVVIFDPSWNPATDAQAVDRAYRIGQQENVVIYRLITCGTVEEK 596

  Fly   634 ILQRQTHKKSLSSTIIDNNESAEKHFTRDDLKDLFTFDANILSDTHDKLKCKRCVQNIQMKPPPE 698
            |.:||..|:||......:.::..::|::.:||:||:.:....|.|..:|      ||:.......
 Frog   597 IYRRQIFKESLIRQTTGDKKNPFRYFSKQELKELFSLEDTRTSSTQIQL------QNMHAAERKT 655

  Fly   699 DTDCTSHLSQWYHCSNNRGLPDNILAQA----------WMDCKCVSFVFHHRSQAQEIV---PSA 750
            ||....|:: :.|.....|:.|:.|..|          :.| :...::.....:|.|:|   ...
 Frog   656 DTRLDEHIA-YLHTLQIFGISDHDLVYANELSSQEDNEYED-EHGQYIEQRVQKAHELVQMESQL 718

  Fly   751 EEEATDQ----------------PEEK-----PESRKRSSTPASDDSADED 780
            .|:..||                ||:.     |..::.||.|.:.|..::|
 Frog   719 NEQLMDQIRKSTEGAWVRQISTAPEKPKKTSLPREKQYSSPPVTVDLTEDD 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	163/531 (31%)
		DEXHc_RAD54A	156..396	CDD:350825	77/246 (31%)
ercc6l	XP_002936822.1	LapB	<21..123	CDD:442196	10/19 (53%)
		HepA	<106..613	CDD:440319	163/532 (31%)
		DEXHc_ERCC6L	107..339	CDD:350759	77/246 (31%)
		MPH1	<482..753	CDD:440728	76/279 (27%)
		Spy	1305..>1359	CDD:443119