Protein Alignment okr and ercc6l2

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001362231.1
• Gene: ercc6l2 / 100127871
• XenbaseID: XB-GENE-952480
• Length: 1397
• Species: Xenopus tropicalis
• Alignment Length: 610
• Identity: 171/610 - (28%)
• Similarity: 292/610 - (47%)
• Gaps: 99/610 - (16%)

  Fly   109 RRPLHDPMACNALVLFHPPAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQREGVRFMYECVEG 173
            ||| |.|:                |...:..|.|.|...:    :..||.:||:|:.|:|:
 Frog    90 RRP-HGPL----------------ENFPLSNTAVSVPYTI----NRYLRDYQRDGITFLYK---- 129

  Fly   174 KRGNFN---GCIMADEMGLGKTLQCVTLVWTLL-RQG---------PE---------CKPTINKA 216
               :|:   |||:.|:||||||:|.:..:..:| ::|         ||         |..:..|.
 Frog   130 ---HFSRSVGCILGDDMGLGKTIQVIAFLAAILGKKGTREDIENNMPEFLLRTVKKVCSSSSPKK 191

  Fly   217 I--VVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTPVLLISYETF 279
            :  :|||.|::.||:.|...|.:.||..:  .|..|::.|..|:|...       .:.|.:|||.
 Frog   192 VFLIVSPLSVLYNWKDELETWGYFRLTLI--HGNKKDSEISRLKQGKF-------EIALTTYETL 247

  Fly   280 RIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVN 344
            |:..:.:...:...|:.||.||:||......|.:..::.|.|:.|:||.:||::.|.:.::::..
 Frog   248 RLCLDEINSIDWSAVVVDEVHRIKNPKARVTQVMKEIRCKVRIGLTGTILQNNMEELWCVMDWAV 312

  Fly   345 PEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKF 409
            |..||:::.||..|.:.:..||..::|::|.....:..|.|...:....:|||..::::.||.|.
 Frog   313 PGYLGSSSQFKEKFSNPVEYGQRHNATKRELATGRKAIQTLANKLSPFFLRRTKALISQQLPKKE 377

  Fly   410 EMVICAKLTAIQLELYTNFLKSDQVR--------------RSLADC-------NEKASLTALADI 453
            :.:|...|:..|..:|...|::..|.              |....|       .|.......:.:
 Frog   378 DRIIFCSLSEFQKAVYQTVLETQDVNLVLQGGEPCSCKSGRKRRKCCYKENMFGESVRTLYFSYL 442

  Fly   454 TTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNY--------KPKDL------NPELSGKFMLL 504
            ..|:|:.:|..|:....:..:|...:.:.|....:        :.||.      ||..|||..:|
 Frog   443 AILRKVANHAALLQTDTSTSKKQEAHIKRVCNEVFSKFPEFVRQSKDAAFETLSNPRYSGKMKVL 507

  Fly   505 DFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDS 569
            ..:|...| :..|||:|.|..|:.||:.|:.:......:.||||....::|.|:|..||..: |.
 Frog   508 QQLLNHCR-KNKDKVLLFSFSTKLLDVLERYSMASGLDYRRLDGNTKAEERMKIVKEFNTMQ-DV 570

  Fly   570 FLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKI 634
            .:.::|:.|||.|||.||||.:.:|||.||||||.||:.|.:|.||.:...::|.|:.|::||.|
 Frog   571 NICLVSTMAGGLGLNFIGANVVVVFDPTWNPANDLQAIDRAYRIGQCRDVKVFRFVSLGTVEEMI 635

  Fly   635 LQRQTHKKSLSSTIIDNNESAEKHF 659
            ..||.:|:.|...:: .:|:|:::|
 Frog   636 YLRQVYKQQLQCAVV-GSENAKRYF 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	5/16 (31%)
		HepA	<156..650	CDD:440319	159/552 (29%)
		DEXHc_RAD54A	156..396	CDD:350825	73/263 (28%)
ercc6l2	NP_001362231.1	Tudor_ERCC6L2	11..66	CDD:410471
		HepA	<78..651	CDD:440319	168/600 (28%)
		DEXHc_ERCC6L2	116..364	CDD:350763	73/263 (28%)
		VIGSSK	<1005..1030	CDD:464308