Protein Alignment gammaTub23C and TUB4

DIOPT Version :10

• Sequence 1: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_013313.1
• Gene: TUB4 / 850909
• SGDID: S000004202
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 478
• Identity: 187/478 - (39%)
• Similarity: 285/478 - (59%)
• Gaps: 27/478 - (5%)

  Fly     1 MPSEIITLQLGQCGNQIGFEFWKRLCLEHGISPSGV--LEDFANDGLDRKDVFFYQADDDHYIPR 63
            |..||||||.|||||.:|...|.:|..||.|...|:  |.|.:.:..|....||.:...:.:.||
Yeast     1 MGGEIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRNKFTPR 65

  Fly    64 AVLLDLEPRVI----NTIMGSVYSKLYNPENVYLSKHGGGAGNNWASGYSQGEKLQEEVFDIIDR 124
            |:::|.||.||    ||..|     .::|.|.:::..|..|||:||:||..|.:.|:::.:.||:
Yeast    66 AIMMDSEPSVIADVENTFRG-----FFDPRNTWVASDGASAGNSWANGYDIGTRNQDDILNKIDK 125

  Fly   125 EADGSDSLEGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSM 189
            |.|.:|:.|||.|.||:|||||||:||.::|.|.||||||::.|:||||.:.  |:||||.||::
Yeast   126 EIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPARS--SEVVVQSYNTI 188

  Fly   190 LTLKRLTTAADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLI 254
            |.|:||...:|:.||.||.:|..|:.......|......|.|:|||:|..|.::|:||||.:::.
Yeast   189 LALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQHTNQLISTIISSVTNSIRFPSYMYSSMS 253

  Fly   255 GLTAPLIPTPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNH 319
            .:.:.|||:|:||||...:||.|||. ||..  :..:..:..|||..||.|.|.:|||.   .|:
Yeast   254 SIYSTLIPSPELHFLSPSFTPFTSDY-IHDD--IAHKGHSSYDVMLDLLDPSNSLVSTA---MNN 312

  Fly   320 HCYISILNIIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPY--VQSN-HRVSGL 381
            ..|.::.|.|.|.|:|.|:.:::.:::.|  .:|..|..:::.|.:.|.|||  :|.| :.|||:
Yeast   313 PTYFNVYNTIIGNVEPRQISRAMTKLQQR--IKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSGM 375

  Fly   382 MLANHTSICSLFERALNQYDKLRKRGAFLDQFRREDIFKDDLN---ELDESRETVDCLVQEYEAA 443
            ||:|.:::.::||.|.|.:||:..:||||:.:...|:|:...|   |..||||.|..|:::|.||
Yeast   376 MLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMEDYVAA 440

  Fly   444 TREDYMQFSVKRGNGPVDSKSED 466
            .::.|:...:......|....||
Yeast   441 EQDSYLDDVLVDDENMVGELEED 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub23C	NP_476804.1	gamma_tubulin	4..440	CDD:276957	179/447 (40%)
TUB4	NP_013313.1	gamma_tubulin	3..437	CDD:276957	179/448 (40%)