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Protein Alignment gammaTub23C and TUBB8B

DIOPT Version :10

Sequence 1:	NP_476804.1	Gene:	gammaTub23C / 33501	FlyBaseID:	FBgn0260639	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001345618.1	Gene:	TUBB8B / 260334	HGNCID:	24983	Length:	444	Species:	Homo sapiens

Alignment Length:	448	Identity:	159/448 - (35%)
Similarity:	260/448 - (58%)	Gaps:	22/448 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLD 68
            ||:..|.||||||||.:||:.:..||.|..:|.....::..|:|.:|..::|....|:|||||:|
Human     3 EIVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYVPRAVLVD 67

  Fly    69 LEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSL 132
            |||..::::....:.:::.|:| ::|.. .|||||||.| |::|.:|.|.|.|::.:||:..|.|
Human    68 LEPGTMDSVHSGPFGQVFRPDN-FISGQ-CGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCL 130

  Fly   133 EGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTT 197
            :||.|.||:.||||||||:.::.::.:.||.::|.|||:.|: .::||.||:|||:.|::.:|..
Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIINTFSILPS-PKVSDTVVEPYNATLSVHQLIE 194

  Fly   198 AADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIP 262
            .||....:||.||..|....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|
Human   195 NADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   263 TPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILN 327
            .|:|||.|.|:.||||..   :||   .|..||.::.:::...||||.:..|   .|.||:::..
Human   260 FPRLHFFMPGFAPLTSRG---SQQ---YRALTVAELTQQMFDAKNMMAACDP---RHGCYLTVAA 315

  Fly   328 IIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLANHTSICSL 392
            |.:|.:...:|.:.:..|:|:..:.|..|.|.:::.|:....|   ...::|...:.|:.:|..|
Human   316 IFRGRMPMREVDEQMFNIQDKNSSYFADWFPDNVKTAVCDIPP---RGLKMSATFIGNNAAIQEL 377

  Fly   393 FERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATRED 447
            |.....|:..:.:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.|:
Human   378 FTCVSEQFTAMFRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATAEE 432

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.