Protein Alignment gammaTub23C and TUBB

DIOPT Version :10

• Sequence 1: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 148/441 - (33%)
• Similarity: 250/441 - (56%)
• Gaps: 32/441 - (7%)

  Fly    20 EFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLDLEPRVINTIMGSVYSK 84
            :||:.:..||||.|:|.....::..|||..|::.:|....|:|||:|:||||..::::....:.:
Human    39 KFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQ 103

  Fly    85 LYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSLEGFILCHSIAGGTGSG 148
            ::.|:|....:  .|||||||.| |::|.:|.:.|.|::.:||:..|.|:||.|.||:.||||||
Human   104 IFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSG 166

  Fly   149 MGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTTAADSVVVLDNTALNRI 213
            ||:.::.::.:.||.:::.||||.|: .::||.||:|||:.|::.:|....|....:||.||..|
Human   167 MGTLLISKIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 230

  Fly   214 ACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIPTPQLHFLMTGYTPLTS 278
            ....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|.|:|||.|.|:.||||
Human   231 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTS 295

  Fly   279 DSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILNIIQGEVDPTQVHKSLQ 343
            ..   :||   .|..||.::.:::...||||.:..|   .|..|:::..:.:|.:...:|.:.:.
Human   296 RG---SQQ---YRALTVPELTQQVFDAKNMMAACDP---RHGRYLTVAAVFRGRMSMKEVDEQML 351

  Fly   344 RIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLA-----NHTSICSLFERALNQYDKL 403
            .::::..:.|:.|.|.:::.|:....|        .||.:|     |.|:|..||:|...|:..:
Human   352 NVQNKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAVTFIGNSTAIQELFKRISEQFTAM 408

  Fly   404 RKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATREDYMQF 451
            .:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.|:...|
Human   409 FRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATAEEEEDF 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub23C	NP_476804.1	gamma_tubulin	4..440	CDD:276957	143/428 (33%)
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	144/432 (33%)