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Protein Alignment gammaTub23C and TUBA3D

DIOPT Version :10

Sequence 1:	NP_476804.1	Gene:	gammaTub23C / 33501	FlyBaseID:	FBgn0260639	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_525125.2	Gene:	TUBA3D / 113457	HGNCID:	24071	Length:	450	Species:	Homo sapiens

Alignment Length:	471	Identity:	145/471 - (30%)
Similarity:	247/471 - (52%)	Gaps:	35/471 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVL--EDFANDGLDRKDVFFYQADDDHYIPRAVL 66
            |.|::.:||.|.|||...|:..||||||.|.|.:  :.....|.|..:.||.:.....::||||.
Human     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVF 67

  Fly    67 LDLEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSD 130
            :||||.|::.:....|.:|::||.:...|.  .|.||:|.| |:.|:::.:.|.|.|.:.||...
Human    68 VDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRKLADLCT 130

  Fly   131 SLEGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRL 195
            .|:||::.||..||||||..|.:||||:..|.||....|:::| ..::|..||:||||:||....
Human   131 GLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYP-APQVSTAVVEPYNSILTTHTT 194

  Fly   196 TTAADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPL 260
            ...:|...::||.|:..|....|.|:.|:::.:|.|:..|:|..|.:||:...:|.:|......|
Human   195 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259

  Fly   261 IPTPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISI 325
            :|.|::||.:..|.|:.|....:.:||      :|.::.....:|.|.||...|   .|..|::.
Human   260 VPYPRIHFPLATYAPVISAEKAYHEQL------SVAEITNACFEPANQMVKCDP---RHGKYMAC 315

  Fly   326 LNIIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGL-----MLAN 385
            ..:.:|:|.|..|:.::..|:.::..||:.|.||..:|.::...|.|.....::.:     ||:|
Human   316 CMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSN 380

  Fly   386 HTSICSLFERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLVQEYEAATREDYMQ 450
            .|:|...:.|..:::|.:..:.||:..:..|.:   :..|..|:||.:..|.::||..
Human   381 TTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGM---EEGEFSEAREDLAALEKDYEEV------- 435

  Fly   451 FSVKRGNGPVDSKSED 466
                 |...|::::|:
Human   436 -----GVDSVEAEAEE 446

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.