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Protein Alignment gammaTub23C and TUBB4B

DIOPT Version :10

Sequence 1:	NP_476804.1	Gene:	gammaTub23C / 33501	FlyBaseID:	FBgn0260639	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_006079.1	Gene:	TUBB4B / 10383	HGNCID:	20771	Length:	445	Species:	Homo sapiens

Alignment Length:	452	Identity:	158/452 - (34%)
Similarity:	265/452 - (58%)	Gaps:	22/452 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLD 68
            ||:.||.||||||||.:||:.:..||||.|:|.....::..|:|.:|::.:|....|:|||||:|
Human     3 EIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVD 67

  Fly    69 LEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSL 132
            |||..::::....:.:::.|:|....:  .|||||||.| |::|.:|.:.|.|::.:||:..|.|
Human    68 LEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCL 130

  Fly   133 EGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTT 197
            :||.|.||:.||||||||:.::.::.:.||.:::.||||.|: .::||.||:|||:.|::.:|..
Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVE 194

  Fly   198 AADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIP 262
            ..|....:||.||..|....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|
Human   195 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   263 TPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILN 327
            .|:|||.|.|:.||||..   :||   .|..||.::.:::...||||.:..|   .|..|:::..
Human   260 FPRLHFFMPGFAPLTSRG---SQQ---YRALTVPELTQQMFDAKNMMAACDP---RHGRYLTVAA 315

  Fly   328 IIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLANHTSICSL 392
            :.:|.:...:|.:.:..::::..:.|:.|.|.:::.|:....|   ...::|...:.|.|:|..|
Human   316 VFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSATFIGNSTAIQEL 377

  Fly   393 FERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATREDYMQF 451
            |:|...|:..:.:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.|:..:|
Human   378 FKRISEQFTAMFRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATAEEEGEF 436

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.