Protein Alignment gammaTub23C and TUBB4A

DIOPT Version :10

• Sequence 1: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001276052.1
• Gene: TUBB4A / 10382
• HGNCID: 20774
• Length: 495
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 157/467 - (33%)
• Similarity: 269/467 - (57%)
• Gaps: 32/467 - (6%)

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLD 68
            ||:.||.||||||||.:||:.:..||||.|:|.....::..|:|.:|::.:|...:|:|||||:|
Human    54 EIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVD 118

  Fly    69 LEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSL 132
            |||..::::....:.:::.|:|....:  .|||||||.| |::|.:|.:.|.|::.:||:..|.|
Human   119 LEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCL 181

  Fly   133 EGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTT 197
            :||.|.||:.||||||||:.::.::.:.:|.:::.||||.|: .::||.||:|||:.|::.:|..
Human   182 QGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVE 245

  Fly   198 AADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIP 262
            ..|....:||.||..|....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|
Human   246 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 310

  Fly   263 TPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILN 327
            .|:|||.|.|:.||||..   :||   .|..||.::.:::...||||.:..|   .|..|:::..
Human   311 FPRLHFFMPGFAPLTSRG---SQQ---YRALTVPELTQQMFDAKNMMAACDP---RHGRYLTVAA 366

  Fly   328 IIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLANHTSICSL 392
            :.:|.:...:|.:.:..::.:..:.|:.|.|.:::.|:....|   ...:::...:.|.|:|..|
Human   367 VFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAATFIGNSTAIQEL 428

  Fly   393 FERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATREDYMQFSVK 454
            |:|...|:..:.:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.|:
Human   429 FKRISEQFTAMFRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATAEE------- 483

  Fly   455 RGNGPVDSKSED 466
               |..:.::|:
Human   484 ---GEFEEEAEE 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub23C	NP_476804.1	gamma_tubulin	4..440	CDD:276957	151/439 (34%)
TUBB4A	NP_001276052.1	PLN00220	52..478	CDD:215107	152/441 (34%)