Protein Alignment gammaTub23C and TUBB3

DIOPT Version :9

• Sequence 1: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_006077.2
• Gene: TUBB3 / 10381
• HGNCID: 20772
• Length: 450
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 158/451 - (35%)
• Similarity: 262/451 - (58%)
• Gaps: 28/451 - (6%)

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDG---LDRKDVFFYQADDDHYIPRAV 65
            ||:.:|.||||||||.:||:.:..||||.|||   ::..|.   |:|..|::.:|....|:|||:
Human     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPSG---NYVGDSDLQLERISVYYNEASSHKYVPRAI 64

  Fly    66 LLDLEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGS 129
            |:||||..::::....:..|:.|:|....:  .|||||||.| |::|.:|.:.|.|::.:|.:..
Human    65 LVDLEPGTMDSVRSGAFGHLFRPDNFIFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKECENC 127

  Fly   130 DSLEGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKR 194
            |.|:||.|.||:.||||||||:.::.::.:.||.:::.||||.|: .::||.||:|||:.|::.:
Human   128 DCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSIHQ 191

  Fly   195 LTTAADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAP 259
            |....|....:||.||..|....|.:..|::..:|:|||..||..||:||:|..:|.:|..|...
Human   192 LVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVN 256

  Fly   260 LIPTPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYIS 324
            ::|.|:|||.|.|:.|||:..   :||   .|..||.::.:::...||||.:..|   .|..|::
Human   257 MVPFPRLHFFMPGFAPLTARG---SQQ---YRALTVPELTQQMFDAKNMMAACDP---RHGRYLT 312

  Fly   325 ILNIIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLANHTSI 389
            :..:.:|.:...:|.:.:..|:.:..:.|:.|.|.:::||:....|   ...::|...:.|.|:|
Human   313 VATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPP---RGLKMSSTFIGNSTAI 374

  Fly   390 CSLFERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATRED 447
            ..||:|...|:..:.:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.|:
Human   375 QELFKRISEQFTAMFRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATAEE 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub23C	NP_476804.1	PLN00222	1..451	CDD:215108	158/451 (35%)
		gamma_tubulin	4..440	CDD:276957	154/442 (35%)
TUBB3	NP_006077.2	PLN00220	1..447	CDD:215107	158/451 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..450		4/8 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810