DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2975 and AgaP_AGAP009562

DIOPT Version :9

Sequence 1:	NP_608719.1	Gene:	CG2975 / 33481	FlyBaseID:	FBgn0031468	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_310125.4	Gene:	AgaP_AGAP009562 / 1271355	VectorBaseID:	AGAP009562	Length:	470	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	64/263 - (24%)
Similarity:	102/263 - (38%)	Gaps:	58/263 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 TNPPPDILAARLFNETRVLCMVLTSPKTHHTRAIHIKRTWGRRCNKLIFMSTKADKELGSVALNV 133
            |:.|.::        .:::..|.|..|.|..|...:|:||.|....|.:.|...|..:.::|.:|
Mosquito   233 TDDPTEV--------DQIMFAVKTCSKYHKDRVPALKQTWTRYVQHLRYFSDVDDPTIPTIATSV 289

  Fly   134 REGYSNLWPKTRAALQYV-----YKHHFQKYDWFLKADDDTYFIMENLRAFLHAHNFREPVYFGN 193
            ....:....||...||.:     |....|...|.:..||||......|..||..::....:|.|.
Mosquito   290 PNSSAGHCAKTLEILQLIGDELRYNGSLQAIRWVMLVDDDTILSTSALARFLSCYDPGRDLYLGE 354

  Fly   194 KFRQHV--KEG----YMSGGAGYVLSKM---ALHRLIKLGFSNSSICTNRNYGYEDVELGRCLAG 249
            ::...:  .:|    |::||.|.|||..   ||.|..:...::|.         :|:.|..||..
Mosquito   355 RYGYRLLGADGGGYNYVTGGGGIVLSVAILDALQRTCECPSASSP---------DDMILAACLQR 410

  Fly   250 VGVVGGDSRDEQGLSRFIPFSPLHWYPQPPDWYQPLLYYTSPDNSSDCCSNTAISFHYN---NAQ 311
            :|:            |.| .|||....:|.|:...||     |...      .:|||.:   :.|
Mosquito   411 LGI------------RPI-HSPLFHQARPSDYAPELL-----DRRG------TVSFHKHWQIDPQ 451

  Fly   312 EFY 314
            :.|
Mosquito   452 QVY 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2975	NP_608719.1	Galactosyl_T	90..>214	CDD:304462	37/134 (28%)
AgaP_AGAP009562	XP_310125.4	Fringe	237..452	CDD:190308	60/255 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2246
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810