Protein Alignment Syt1 and Syt17

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001390574.1
• Gene: Syt17 / 110058
• MGIID: 104966
• Length: 474
• Species: Mus musculus
• Alignment Length: 349
• Identity: 133/349 - (38%)
• Similarity: 203/349 - (58%)
• Gaps: 35/349 - (10%)

  Fly   152 VDMKSVQL-LGSAYKEKVQPD------------------MEELTENAEEGD---EEDKQSEQKLG 194
            :|:|.|:. :.||.||.:||.                  :..|..|.::.|   :|:..|:.:||
Mouse   122 IDIKPVEFGVLSAKKESIQPSVLRRTYTPDDYFRKFEPRLYSLDSNLDDVDSLTDEEIMSKYQLG 186

  Fly   195 RLNFKLEYDFNSNSLAVTVIQAEELP--------ALDMGGTSDPYVKVYLLPDKKKKFETKVHRK 251
            .|:|..:||...|.|.|.||:|.:||        ..|| ..|:||||:.||||:|...:|.|.||
Mouse   187 MLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM-AHSNPYVKICLLPDQKNSKQTGVKRK 250

  Fly   252 TLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVS 316
            |..|||.|.:||: :|:.:|..:||:..:.|||:||:|..||:|.||||.:||.:....|:.|
Mouse   251 TQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKAL-- 312

  Fly   317 VEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKT 381
            :.....:.:||::..||.|:|:||:|.|.|:.||.|.:.||...|||:|||.::...|.:|.|||
Mouse   313 IPSSQNEVELGELLLSLNYLPSAGRLNVDIIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKT 377

  Fly   382 SIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTG-TELRHWSD 445
            |..:.|::|:|||||||:||.|:::...||.||..::...:::.|||.::|...:| :|..||..
Mouse   378 SFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRR 442

  Fly   446 MLASPRRPIAQWHTLKDPEETDEI 469
            ||.:.|..:.|||:|:...|.|.:
Mouse   443 MLNTHRTAVEQWHSLRSRAECDRV 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	3/9 (33%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	58/131 (44%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	58/135 (43%)
Syt17	NP_001390574.1	C2A_Synaptotagmin-15-17	186..314	CDD:176036	57/131 (44%)
		C2B_Synaptotagmin-17	323..457	CDD:176055	57/133 (43%)