Protein Alignment Syt1 and tc2n

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_009305708.1
• Gene: tc2n / 101885722
• -ID: -
• Length: 465
• Species: Danio rerio
• Alignment Length: 342
• Identity: 69/342 - (20%)
• Similarity: 134/342 - (39%)
• Gaps: 57/342 - (16%)

  Fly   146 GKGKKGVDMKSVQLLGSAYKEKV--QPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNS 208
            |:.::...:.|:|...|:.::..  ...:|.:|.:   |||.|::.    |::...|:|:.....
Zfish   157 GRVERYDSVSSIQSSTSSVQDSFGSSRSLESITLS---GDERDREP----GKVCVHLKYEAAVEQ 214

  Fly   209 LAVTVIQAEELPALD-------MGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSL 266
            :.:|:::..:|...:       :|      ||..:..:|..:|::.:...:...||.|||.| :|
Zfish   215 VWITLVKCTDLSVYNERVEQQKIG------VKGVITVNKPVRFKSTLKEASEDTVFMETFVF-TL 272

  Fly   267 PYADAMNKTLVFAIFDFDRFSKHD----QIGEVKVPLCTIDL----AQTIEEWRDLVSVEGEGGQ 323
            .........||.      |...|.    .:||     |.:.|    .|..:.|.       |...
Zfish   273 NLEQIRRSALVL------RLQAHTPRKRTLGE-----CVLSLRSLGPQETKHWL-------EFKH 319

  Fly   324 EKLGDIC-----FSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKT-S 382
            .....:|     .:|.:.|...::.:.||..:||...........:||:.::..||.|.|:|| :
Zfish   320 PSKTHVCHAELQLALCFQPVNSRMQLQILSTQNLPSSSSPLTQSYFVKVDLLGEGKFLLKRKTKA 384

  Fly   383 IKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTE-LRHWSDM 446
            :|.......:.|...|.:. .|...:.|.|.:.....:.....:|:.:|....:..| :..|.|.
Zfish   385 VKSSGGQVQWGEVLHFPIT-SQDHNLQLSVKLYSRSSVRRKHLLGQVLLSLDSSSPEAVEQWKDA 448

  Fly   447 LASPRRPIAQWHTLKDP 463
            :|:|.:.:..||.:..|
Zfish   449 MANPEKVVTSWHRVSRP 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	3/14 (21%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	27/138 (20%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	30/141 (21%)
tc2n	XP_009305708.1	C2	215..317	CDD:472691	24/126 (19%)
		C2B_Tac2-N	328..462	CDD:176074	29/134 (22%)