Protein Alignment Syt1 and doc2b

DIOPT Version :10

• Sequence 1: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_002934390.1
• Gene: doc2b / 100496262
• XenbaseID: XB-GENE-6032690
• Length: 394
• Species: Xenopus tropicalis
• Alignment Length: 349
• Identity: 124/349 - (35%)
• Similarity: 183/349 - (52%)
• Gaps: 31/349 - (8%)

  Fly   143 TKDGKGKKGVDMKSVQLLGSAYKEKVQPDMEEL-----------TENAEEGDEEDKQSEQ--KLG 194
            |:....|..|...||....::.:|  :.|:::|           .::.||||.:...|:.  .||
 Frog    48 TRANSLKSNVSQPSVSPCETSKEE--EEDVDKLFGAYGAASTAPAKHEEEGDLDGYDSDDCTTLG 110

  Fly   195 RLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLP--DKKKKFETKVHRKTLSPVF 257
            .|:|.|.||..:|:|..|:.:|:.|..:|..|.||||||::|||  .|..|..||..|.||:|.:
 Frog   111 TLDFSLLYDQENNALHCTINKAKGLKPMDHNGLSDPYVKLHLLPGASKANKLRTKTLRNTLNPTW 175

  Fly   258 NETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQT------IEEWRDLVS 316
            |||.|:..:...|.:.|||..::.|.|:|..::.|||.::||..:...||      :|:...:..
 Frog   176 NETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRIPLKKLKPNQTKNFSICLEKQLPIDK 240

  Fly   317 VEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKT 381
            .|.:..:|: |.|..||:|......|.|.|:...:|..||..|.||||||..:..:..:..|.||
 Frog   241 TEDKSLEER-GRILISLKYSSQKSGLLVGIIRCAHLAAMDANGYSDPYVKTYLKPDEDKKSKHKT 304

  Fly   382 SIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEP-IGRCILGCMGTGTELRHWSD 445
            ::||.||||.:||.|.:|:....:.|..|.|||.||| ||.|.. ||..:||....|..|:||.|
 Frog   305 AVKKKTLNPEFNEEFCYEIKHSDLAKKTLEVTVWDYD-IGKSNDFIGGVVLGINAKGERLKHWFD 368

  Fly   446 MLASPRRPIAQWHTLKDPEETDEI 469
            .|.:..:.|.:||||     |:|:
 Frog   369 CLKNKDKKIERWHTL-----TNEL 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	5/17 (29%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	50/131 (38%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	56/135 (41%)
doc2b	XP_002934390.1	C2A_Rabphilin_Doc2	109..232	CDD:176000	49/122 (40%)
		C2B_Rabphilin_Doc2	251..383	CDD:176030	54/132 (41%)