Protein Alignment aph-1 and Aph1a

DIOPT Version :10

• Sequence 1: NP_608710.1
• Gene: aph-1 / 33467
• FlyBaseID: FBgn0031458
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: XP_006233039.1
• Gene: Aph1a / 365872
• RGDID: 1311546
• Length: 265
• Species: Rattus norvegicus
• Alignment Length: 243
• Identity: 114/243 - (46%)
• Similarity: 164/243 - (67%)
• Gaps: 12/243 - (4%)

  Fly     6 FFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISS-LWYALIPLKE--------- 60
            ||||||:||||.||||:.|:|.||:|:|||:|.|||||:|||::| :|:.|:.:.:
  Rat     6 FFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYG 70

  Fly    61 FLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRVTDNKHILAYVSGLGFGIISGMFALV 125
            .|.||...||..||.||:..|::|:..::||.:::||.|...:...:||||||.||||||:|:::
  Rat    71 LLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYVSGLSFGIISGVFSVI 135

  Fly   126 NVLADMSGPGTMGLKGGTELFFVTSAAQALSIILLHTFWSVIFFNAFDTNNYIHIGYVVFSHLFV 190
            |:|||..|||.:|:.|.:..:|:|||....:||||||||.|:||:|.:...|..:|.||.|||..
  Rat   136 NILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLT 200

  Fly   191 SLITLLNANELYTTTLLINYLVTILTGVLAFRVAGGTSRSFRKFITCQ 238
            |.:|.|  |..|..:||..|.||:..|:.||..|||:.||.::.::|:
  Rat   201 SGLTFL--NPWYEASLLPIYAVTVSMGLWAFVTAGGSLRSIQRSLSCR 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aph-1	NP_608710.1	Aph-1	3..225	CDD:461830	108/228 (47%)
Aph1a	XP_006233039.1	Aph-1	3..233	CDD:461830	108/228 (47%)