Protein Alignment: aph-1 and Aph1a

• Sequence 1: NP_001259963.1
• Gene: aph-1
• FlyBaseID: FBgn0031458
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: XP_006233039.1
• Gene: Aph1a
• RGDID: 1311546
• Length: 265
• Species: Rattus norvegicus
• Alignment Length: 243
• Identity: 114/244 (47%)
• Similarity: 164/244 (67%)
• Gaps: 12/244 (5%)

  Fly     6 FFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISS-LWYALIPLKE--------- 60
            ||||||:||||.||||:.|:|.||:|:|||:|.|||||:|||::| :|:.|:.:.:
  Rat     6 FFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDRSDARLQYG 70

  Fly    61 FLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRVTDNKHILAYVSGLGFGIISGMFALV 125
            .|.||...||..||.||:..|::|:..::||.:::||.|...:...:||||||.||||||:|:::
  Rat    71 LLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYVSGLSFGIISGVFSVI 135

  Fly   126 NVLADMSGPGTMGLKGGTELFFVTSAAQALSIILLHTFWSVIFFNAFDTNNYIHIGYVVFSHLFV 190
            |:|||..|||.:|:.|.:..:|:|||....:||||||||.|:||:|.:...|..:|.||.|||..
  Rat   136 NILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFDACERRRYWALGLVVGSHLLT 200

  Fly   191 SLITLLNANELYTTTLLINYLVTILTGVLAFRVAGGTSRSFRKFITCQ 238
            |.:|.|  |..|..:||..|.||:..|:.||..|||:.||.::.::|:
  Rat   201 SGLTFL--NPWYEASLLPIYAVTVSMGLWAFVTAGGSLRSIQRSLSCR 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aph-1	NP_001259963.1	Aph-1	2..225	CDD:283708	109/229 (48%)
Aph1a	XP_006233039.1	Aph-1	3..233	CDD:283708	109/229 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C290042045
eggNOG	1	0.900				E1_KOG3972
Hieranoid	1	1.000
Homologene	1	1.000				H9345
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3358
OMA	1	1.010
OrthoDB	1	1.010				D1085102at2759
OrthoFinder	1	1.000				FOG0001574
OrthoInspector	1	1.000				T618918
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR12889
Phylome	1	0.910		0.800	Consistency score
TreeFam	0	0.000	Not matched by this tool.
	11	10.910