back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Obsc and bt

DIOPT Version :10

Sequence 1:	NP_001097440.1	Gene:	Obsc / 3346201	FlyBaseID:	FBgn0053519	Length:	4218	Species:	Drosophila melanogaster
Sequence 2:	NP_001162825.1	Gene:	bt / 43814	FlyBaseID:	FBgn0005666	Length:	8933	Species:	Drosophila melanogaster

Alignment Length:	5781	Identity:	1020/5781 - (17%)
Similarity:	1718/5781 - (29%)	Gaps:	2322/5781 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FVSRDYQAQS-----LATDEISVSRGDLVELISSKASE-----------KSRCFVRMFDSGDSPK 57
            ||.|..::||     .||:|:.....:|...:..|..:           |..|.::.....|
  Fly  3559 FVMRAQRSQSGKYIIKATNEVGEDEAELEVTVLGKPGKPKGPLQVNDITKHSCKLKWEKPDD--- 3620

  Fly    58 EGWVPIDILEFN----------PTMSSSN------GKESGDA-EFRKLTILRELVETEEEFSRDL 105
            :|..|||..|..          |...|:.      |...|.| :||...:      .:|..|.||
  Fly  3621 DGGSPIDYYEIEKLDPHTGQWLPCGKSTEPEAKVIGLHEGKAYKFRVRAV------NKEGESEDL 3679

  Fly   106 LHVVEKYIKGIDKPVVPRSVRDNKDIIFCNFLQIAEFHNNVLKEGLKCYSNQPNMVAKTFLRLER 170
                     ..:||::.::..|..|                          :|.....|
  Fly  3680 ---------ETEKPIIAKNPYDEPD--------------------------RPGKPEPT------ 3703

  Fly   171 DFDKHVVYCQNEPLAQDYLGSSPDAKKYFQELSKQLGDDKSLAEHLKLPIQRINDYQLLFKDFIK 235
            ::||..|....:|...|  |.:| .:||..::..:.|  ::..:...:|..:.|......::..:
  Fly  3704 NWDKDFVDLAWDPPKND--GGAP-IQKYVIQMRDKSG--RAWVDSATVPGDKCNGTVTGVEEGHE 3763

  Fly   236 YSLSL----KENVKDLERALELMLSVPSRAYDNRFLS---SIEGCRGNIYKLGRLLLH------- 286
            |...:    |....|.....:.:::.|      |||.   ..:..:..|.:.|: :||
  Fly  3764 YEFRIVAVNKAGPSDPSDVSKSVIAKP------RFLKPHIDRKNLQKKIMRSGQ-MLHIDALIKA 3821

  Fly   287 ------AWC-NVVDKEGKAH------DRYCFLFKSRILVTKVRKISENRSVFIL--QNIVKLPLC 336
                  .|. |..:.:...|      |     :|:..::.||::  .:|.::|:  :|.......
  Fly  3822 EPPAKVTWTYNKTEIKTSDHIKIENED-----YKTTFIMPKVKR--ADRGIYIVTAKNDSGSDTV 3879

  Fly   337 NIELK----------------ADEKQIHLSLKAPEANSFLPID-----------------IKPHG 368
            .:||:                ...:.:||..:.||.:...||:                 :....
  Fly  3880 EVELEVLCKPSKPKGPLAVSNVTAETLHLKWEKPEDDGGDPIEQYLVERMDTETGRWVPVLTTKT 3944

  Fly   369 PEAHLTWFNEISSHINQDVTLQEHNADDLKVDASQIASESE-LILHLPQRAEAHDPNLSVRPSDV 432
            |||.:|...|...::             .:|.|.....||| |:..:|.:|:        .|.|.
  Fly  3945 PEADVTGLTEGKEYL-------------FRVKAVNSEGESEPLVTDIPTKAK--------NPFDA 3988

  Fly   433 AENYFLSKETKERLQHEQQELLKLEQEAIELYKKQQSSKSVSSKTESVEITSSQVKSSSEVRKVV 497
            |:.     ..|.::.........|:..|.|    .....|::.     .|...:..::.:.:|.:
  Fly  3989 ADT-----PGKPQIVDWSGNHCDLKWRAPE----DDGGASITG-----YIVERKDPNTGKWQKAL 4039

  Fly   498 SPPPPP-QAQVKEVTP-------VKVVSSPPPPKEITPAKVATPPPQPQVVTSPVKEVAPPPQPR 554
            ....|. :|:|.::..       :..|:.....|          |.:|....:.....|||...|
  Fly  4040 ETSTPDCKARVNDLIAGNKYQFRIMAVNKAGKSK----------PSEPSDQMTAKDRFAPPKIDR 4094

  Fly   555 AVASPAKEVTPSQSEPVKAPSPIK-EVRKEVPPSAS----HSK------------EVEALVATEI 602
               :..|::|      :||...|: :::....|.|:    |:|            ::|:     .
  Fly  4095 ---TNIKDIT------IKAGQHIRFDIKVSGEPPATKVWLHNKARLENDDSNYNIDMES-----Y 4145

  Fly   603 RESLTETRSTVVESGQSSEIREEIVVTEESSLEGKQVVALEREPSPCSIP-----------KIQV 656
            |..||...|....||:.:...|.....:|:|.|   |:.|:: |.|...|           |::.
  Fly  4146 RTKLTVPISKRFHSGKYTLKAENESGRDEASFE---VIVLDK-PGPPEGPLRVTDVHKEGCKLKW 4206

  Fly   657 YRPVECENPVVTKHKPIELKDIVG--------YSESL--------------------RDGDTAP- 692
            ..|:: :..:...|..||..|:..        :.||.                    .:|::.|
  Fly  4207 NAPLD-DGGLPIDHYIIEKMDVESGRWLPSGRFKESFAELNNLEPSHEYKFRVLAVNTEGESEPL 4270

  Fly   693 -------------AGGSPGRQQGYSANITDHASLTIWNNRLANIAGDRSGANQHLQQSGPPPPPI 744
                         ..|.||..:....: .||..| :|.                        |||
  Fly  4271 TGEQSVIAKNPFDEPGKPGTPEAVDWD-KDHVDL-VWR------------------------PPI 4309

  Fly   745 PPNFTRMPGFFQ----------------PLPLIAYE--TTIEIL--------IVKARPPSPPPPP 783
            ....:.:.|:..                .:|.:..|  .|:..|        .|||...:.|..|
  Fly  4310 NDGGSPITGYVVEKREKGTDKWIKGTEITIPCLGEECKATVPTLNENCEYEFRVKAINAAGPGEP 4374

  Fly   784 PPTIKRVLVHTESLEQK-------TQNFFEG--------IYDAASSDTSLRNAKQKIRSIKSTVL 833
            ....|.::.....|..|       |.||..|        |....:.|.:.   .|..:|:::|..
  Fly  4375 SDASKPIITKPRKLAPKIDRKNIRTYNFKSGEPIFLDINISGEPAPDVTW---NQNNKSVQTTSF 4436

  Fly   834 KSKDSTNY----------AQDT-VQKAKARDF---------LHIFTPPVKKRPIYEIVEEPVNIF 878
            ...::..|          .:|| :.|..|.:|         ::|.|.|.|.       |.|:.:.
  Fly  4437 SHIENLPYNTKYINNNPERKDTGLYKISAHNFYGQDQVEFQINIITKPGKP-------EGPLEVS 4494

  Fly   879 ELEGDYTESIADDFREPSADFEARGQSVGGMDDYYSGYSRASTRRYETKTRDYDRGTSYDSTVER 943
            |:..|..:.   .:::|..|        ||          .....|..:..|.|.|.
  Fly  4495 EVHKDGCKL---KWKKPKDD--------GG----------EPVESYLVEKFDPDTGI-------- 4530

  Fly   944 SQYGISSRRDRSSVDKVEARSSLLATGRTESRAASRAESRAESRASYSV------AESRAGIRSS 1002
                                  .|..||::.             ..|:|      .:.:..:::.
  Fly  4531 ----------------------WLPVGRSDG-------------PEYNVDGLVPGHDYKFRVKAV 4560

  Fly  1003 SRLQEDRPLRSVDKPVVVKMLKSVQVEPGETAHFEIQFKDQPGLVTWLKDNKPLEDRLADRITQT 1067
            ::..|..||.::.. ::.|...||..:||           .|....|.. || :|....:..:..
  Fly  4561 NKEGESEPLETLGS-IIAKDPFSVPTKPG-----------VPEPTDWTA-NK-VELAWPEPASDG 4611

  Fly  1068 AAPMNSYRLDIKN--------CSETDAGTYTIRAQSASETTTVSAQLAV----GQAPGHDETKTN 1120
            .:|:..|.:::|:        ..||::.|.|...|...|......::..    |.:...|.:|..
  Fly  4612 GSPIQGYIVEVKDKYSPLWEKALETNSPTPTATVQGLIEGNEYQFRVVALNKGGLSEPSDPSKIF 4676

  Fly  1121 T-EPAFLV------SLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDY 1178
            | :|.:|.      :|::..:...|..:....|.|:|.|:|: :|.....|::...: .|...||
  Fly  4677 TAKPRYLAPKIDRRNLRNITLSSGTALKLDANITGEPAPKVE-WKLSNYHLQSGKNV-TIETPDY 4739

  Fly  1179 LGFYELVIADVQKTDAGTYSCKATNKHGEANCEAIATTVEDK--NPFGALSGQILPAGEKPV-FQ 1240
              :.:|||...|::|:|.|...|||..|: :...:...:.||  .|.|.|  ||....::.. .:
  Fly  4740 --YTKLVIRPTQRSDSGEYLVTATNTSGK-DSVLVNVVITDKPSPPNGPL--QISDVHKEGCHLK 4799

  Fly  1241 WKRNGEE-FDPEERFKVLFGEDEDSLALVFQHVKPE-DAGIYTC--------VAQTSTGNISCSA 1295
            |||..:: ..|.|.|::      |.|       :|| ...|.:|        |...|.||
  Fly  4800 WKRPSDDGGTPIEYFQI------DKL-------EPETGCWIPSCRSTEPQVDVTGLSPGN----- 4846

  Fly  1296 ELSVQGAIQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFP-KP----AVQWKHD------ 1349
              ..:..:..:|.|.|...||          |..:|:.......| ||    |..|..|
  Fly  4847 --EYKFRVSAVNAEGESQPLV----------GDESIVARNPFDEPGKPENLKATDWDKDHVDLAW 4899

  Fly  1350 -------GE-----VIQVDDRH-KFMYEDEESMSLVIKNV-----DTVDAGVY--TIEAINELGQ 1394
                   |.     :|:..|:: |:    |.::.:.....     |.|:...|  .:.|:|..|.
  Fly  4900 TPPLIDGGSPISCYIIEKQDKYGKW----ERALDVPADQCKATIPDLVEGQTYKFRVSAVNAAGT 4960

  Fly  1395 DESSIN---LVVKA---PPKIKK--ITDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESN 1451
            .|.|.:   ::.||   ||.|.:  :.::...||::...:.:|.|.|.|..:.....|:|.::.|
  Fly  4961 GEPSDSTPPIIAKARNKPPIIDRSSLVEVRIKAGQSFTFDCKVSGEPAPQTKWLLKKKEVYSKDN 5025

  Fly  1452 VKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSKP--------VIVK 1508
            ||:::......|     :|.....|.:|.|::.|.|...:.|.....||..||        |...
  Fly  5026 VKVTNVDYNTKL-----KVNSATRSDSGIYTVFAENANGEDSADVKVTVIDKPAPPNGPLKVDEI 5085

  Fly  1509 NFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDA 1573
            |.||..:|....:......||.|...||    |||..:...:..|   ||....||:.|.|....
  Fly  5086 NSESCTLHWNPPDDDGGQPIDNYVVEKL----DETTGRWIPAGET---DGPVTALKVGGLTPGHK 5143

  Fly  1574 GKYTVKATNEHGSA---TSSTQLLIKCAPEFTHKLKNITVAEGDSN-VELVVGVDAYPRPHAKWY 1634
            .|:.|:|.|..|::   |::..::.|...:...|....|:.:.|.. |:|     .:.||.|
  Fly  5144 YKFRVRAKNRQGTSEPLTTAQAIIAKNPFDVPTKPGTPTIKDFDKEFVDL-----EWTRPEA--- 5200

  Fly  1635 IDGIE-----IDEKRNDF-----RHVEEGNDFKLIMN----QVATNMQGNYTCKIMNDYG----- 1680
             ||..     :.|||:.|     :..|..:|   |.|    .:...::..:..:.:|..|
  Fly  5201 -DGGSPITGYVVEKRDKFSPDWEKCAEISDD---ITNAHVPDLIEGLKYEFRVRAVNKAGPGSPS 5261

  Fly  1681 -KLEDNCVVTVNCKPKVKRG-LKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKIS 1743
             ..|.:.....|..||:.|. :.:::::.|..|..:|.|..||.....|..:|:.|....|:|||
  Fly  5262 DATETHVARPKNTPPKIDRNFMSDIKIKAGNVFEFDVPVTGEPLPSKDWTHEGNMIINTDRVKIS 5326

  Fly  1744 RDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQ------TVTK-T 1801
            ....|.:...|.   |:..|.|.|.:.|.|..|......||.:|  :|.|:.:      .|:| :
  Fly  5327 NFDDRTKIRILD---AKRSDTGVYTLTARNINGTDRHNVKVTIL--DAPSVPEGPLRNGDVSKNS 5386

  Fly  1802 LIATTEEPEEGAVPEIVH--VDVFQQHSYESVPLKYEVIATGIPKPEAIWYHD------------ 1852
            ::.....|::....||.|  |:.....:...||:. :...|.|.....|..||
  Fly  5387 IVLRWRPPKDDGGSEITHYVVEKMDNEAMRWVPVG-DCTDTEIRADNLIENHDYSFRVRAVNKQG 5450

  Fly  1853 -------GKPIT-------PDK--HTAITVDGDHYKLEVQSLDLVDAG----EYKVVVQNKVGE- 1896
                   .:|||       |||  ....|..|.|:.....|....|.|    .|.:..:.|.|:
  Fly  5451 QSQPLTTSQPITAKDPYSHPDKPGQPQATDWGKHFVDLEWSTPKRDGGAPISSYIIEKRPKFGQW 5515

  Fly  1897 -----------KSHQGELSLSGIAEYRKPILTQG-------PG------------------LKDI 1925
                       |:|..||:..|..|:|...:.:|       |.                  |.||
  Fly  5516 ERAAVVLGDNCKAHVPELTNGGEYEFRVIAVNRGGPSDPSDPSSTIICKPRFLAPFFDKSLLNDI 5580

  Fly  1926 KVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIK 1990
            .|:.|.::...:...|.|.|.|..|.:|:.:...:.         .|:||.|...|..|:.:...
  Fly  5581 TVHAGKRLGWTLPIEASPRPLITWLYNGKEIGSNSR---------GESGLFQNELTFEIVSSLRS 5636

  Fly  1991 DSGRYELKVKNKYG--------------------------------------------------- 2004
            |.|||.|.:||::|
  Fly  5637 DEGRYTLILKNEHGSFDASAHATVLDRPSPPKGPLDITKITRDGCHLTWNVPDDDGGSPILHYII 5701

  Fly  2005 ---ELVTSGWID----------------------------------------------------- 2013
               :|..|.|.|
  Fly  5702 EKMDLSRSTWSDAGMSTHIVHDVTRLVHRKEYLFRVKAVNAIGESDPLEAVNTIIAKNEFDEPDA 5766

  Fly  2014 ----------------------------------------------------------------- 2013

  Fly  5767 PGKPIITDWDRDHIDLQWAVPKSDGGAPISEYIIQKKEKGSPYWTNVRHVPSNKNTTTIPELTEG 5831

  Fly  2014 ------------------------VLAKPE------ISGLNDTKCLPGDTICFEALVQ--ANPKP 2046
                                    ::|||.      |:.||:.:...|  :.|...:.  ..|.|
  Fly  5832 QEYEFRVIAVNQAGQSEPSEPSDMIMAKPRYLPPKIITPLNEVRIKCG--LIFHTDIHFIGEPAP 5894

  Fly  2047 KVSWTRGNENLCNHE----------------NCE------------------------VIAD--- 2068
            :.:||..:..|.:::                ||:                        |:.|
  Fly  5895 EATWTLNSNPLLSNDRSTITSIGHHSVVHTVNCQRSDSGIYHLLLRNSSGIDEGSFELVVLDRPG 5959

  Fly  2069 ----------------------------------------------------------------- 2068

  Fly  5960 PPEGPMEYEEITANSVTISWKPPKDNGGSEISSYVIEKRDLTHGGGWVPAVNYVSAKYNHAVVPR 6024

  Fly  2069 ----------------------------------------------VDADKYRLVFQSVSPCEDG 2087
                                                          .|:||..:..:...|..:|
  Fly  6025 LLEGTMYELRVMAENLQGRSDPLTSDQPVVAKSQYTVPGAPGKPELTDSDKNHITIKWKQPISNG 6089

  Fly  2088 -------------------------------------------KYTITATNSEGRAAVD-----F 2104
                                                       :|.|:|.|:.|.....     |
  Fly  6090 GSPIIGYDIERRDVNTGRWIKINGQPVPTAEYQDDRVTSNHQYQYRISAVNAAGNGKTSEPSAIF 6154

  Fly  2105 NLAVLVEKPTFIVQ---PESQSIHDYRPVSTKVLVHGVPLPTIEWFKDD------KPINYEAINK 2160
            |...|.|||.|...   .:...:....||:..:.:.|.|.|||||.:.|      |.|:||
  Fly  6155 NARPLREKPRFYFDGLIGKRIKVRAGEPVNLNIPISGAPTPTIEWKRGDLKLEEGKRISYE---- 6215

  Fly  2161 PGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFK------------- 2212
                           |:...::..|......|.|.||..|.||.|...|..:
  Fly  6216 ---------------TNSERTLFRIDDSNRRDSGKYTVTAANEFGKDTADIEVIVVDKPSPPEGP 6265

  Fly  2213 LAMLSLAPSFVK------KLDNALDV--------------------------------------- 2232
            |:....||..:.      |.|...|:
  Fly  6266 LSYTETAPDHISLHWYSPKDDGGSDITGYIIEFTEFGVDDWKPVPGTCPNTNFTVKNLVEGKKYV 6330

  Fly  2233 --------------LQGEPLVLECCVD--GSP-LPTV---------------------------- 2252
                          |:|:|::.:...|  |:| .||:
  Fly  6331 FRIRAENIYGASEALEGKPVLAKSPFDPPGAPSQPTISAYTPNSANLEWHPPDDCGGKPITGYIV 6395

  Fly  2253 -------QWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCA-- 2308
                   :|:|..:...|:.|..:|...|| .:.|......|::|.     .:|......:.|
  Fly  6396 ERRERGGEWIKCNNYPTPNTSYTVSNLRDG-ARYEFRVLAVNEAGP-----GHPSKPSDPMTAEH 6454

  Fly  2309 --------VAVKPE---------------------------EMQPKFLK--------PITSQTVV 2330
                    ...||:                           ||:||..|        ||.|....
  Fly  6455 QRYRPDPPEPPKPDRITRNGVTLSWRPPRTDGKSRIKGYYVEMRPKNGKDWKTVNDIPINSTVYT 6519

  Fly  2331 V---------------------------GEPLKLEAQ---------------------------V 2341
            |                           .:|:.:|.|                           .
  Fly  6520 VPSLKEGEEYSFRVVAENEVGRSDPSKPSQPITIEEQPNKPCMELGKVRDIVCRAGDDFSIHVPY 6584

  Fly  2342 TGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEGVSKV 2406
            ..||.|...||.:..:|..:..:: .:..:....:::..::..|:|.|:..:.|..|.......|
  Fly  6585 LAFPKPNAFWYSNDNMLDDNNRVH-KHLTDDAASVVVKNSKRADSGQYRLQLKNTSGFDTATINV 6648

  Fly  2407 EIVPKESKPV-----------------------------FVAELQDA-----SSIEGFPV----- 2432
            .::.:.|.|.                             ::.|.::|     |.:..|..
  Fly  6649 RVLDRPSPPTRLRADEFSGDSLTLYWNPPNDDGGSAIQNYIIEKKEARSSTWSKVSSFCTVPFVR 6713

  Fly  2433 --------KMDIKVVGNPK---------------------PKLQWFHNGHEIKPDASHIAIVENP 2468
                    :.|.:|:...|                     |......:|.:...|:..||..:..
  Fly  6714 IRNLVLNKEYDFRVIAENKYGQSDPANTSEPILARHPFDIPNTPGIPHGIDSTEDSITIAWTKPK 6778

  Fly  2469 DNSSS----LIIEKTAPGD-----------------------SGLYE--VIAQNPEGSTA--SKA 2502
            .:..|    .||||....|                       :..||  |.|.|..|.:|  ..:
  Fly  6779 HDGGSPITGYIIEKRLLSDDKWTKAVHALCPDLSCKIPNLIENAEYEFRVAAVNAAGQSAYSGSS 6843

  Fly  2503 KLYVAPKADETATEEAPQFVS--ALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERL 2565
            .|....:     ...||:..|  ::||:....|.|..::.|:.::|.|...||.:|:.:.|.||:
  Fly  6844 DLIFCRR-----PPHAPKITSDLSIRDMTVIAGDEFRITVPYHASPRPTASWSLNGLEVIPGERI 6903

  Fly  2566 LMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKVYKPP--------------- 2615
            ....:........|.|:..::|:||..|.|..|.|:::|:..|.....||
  Fly  6904 KFDSNDYASMYYNKSAKRDETGSYTITLTNNKGSDTASCHVTVVDRPLPPQGPLNAYDITPDTCT 6968

  Fly  2616 ----------------------------------------------------------------- 2615

  Fly  6969 LAWKTPLDDGGSPITNYVVEKLDNSGSWVKISSFVRNTHYDVMGLEPHYKYNFRVRAENQYGLSD 7033

  Fly  2616 -----------------------------------VFTQKISD---------------------- 2623
                                               ::|:.:||
  Fly  7034 PLDIIEPIVAKHQFTVPDEPGQPKVIDWDSGNVTLIWTRPLSDGGSRIQGYQIEYRDILNDSSWN 7098

  Fly  2624 ----------------------QQQVFGNNA-------------------KIP-------VTVSG 2640
                                  :.::...||                   .:|       ||..|
  Fly  7099 AYDYIIKDTKYQLYNLINGSEYEFRIKAKNAAGLSKPSSPSLRFKLKGKFTVPSPPGAPQVTRVG 7163

  Fly  2641 VPYPDLEWYFQDKPI----------------------PKSEKYSIKNDGDHHMLIVNNCEKGDQG 2683
            ..|.||:|   :||:                      .|...|::.   |....::|..|.||.
  Fly  7164 KNYVDLKW---EKPLRDGGSRITGYIIERRDIGGAVWVKCNDYNVL---DTEYTVMNLIEMGDY- 7221

  Fly  2684 VYKCIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEG-----------MVAKF- 2736
            .::..|.|..|                  ||||.:....|..|::..|           .||.|
  Fly  7222 EFRVFAVNSAG------------------RSEPSLCTMPIKVCEVLGGKKPDWITRLQDKVAPFG 7268

  Fly  2737 -----TACATGYPEPEVEWFKNDQKL-FPSDRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFN- 2794
                 ...|:|.|.|...|.:|.::: ....|...| ..:|:.||.|.||...|.|.|:|...|
  Fly  7269 KDYTLQCAASGKPSPTARWLRNGKEIQMNGGRMTCD-SKDGVFRLHISNVQTGDDGDYTCEAMNS 7332

  Fly  2795 ---------------------------PYGDDICHAELFYDS-------LDSQQKPLEDQYTD-- 2823
                                       |.||: ...::||..       |....:.:.|...|
  Fly  7333 LGFVNTSGYLKIGSPPIINRCPSELKLPEGDN-SKIKIFYSGDQPLTVILKKNNEVICDSNDDTH 7396

  Fly  2824 -----FKKY---------KKSGAP-----------------------PPLSEGPI-ISRMTDRGL 2850
                 |..|         |..|.|                       |....||: ||.:.....
  Fly  7397 VKVNIFDDYVAIYIRNIVKSDGGPYQIEFTNESGSATGEFYVHITGMPSAPTGPMGISYINKNSC 7461

  Fly  2851 LLSWNPSVPLTPRYP-----ITYQIEMMDLPEGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVE 2910
            :|:|.|     |.|.     ..|.||..|:....|.|:.:..:..|.:::.|...::|.|||...
  Fly  7462 MLNWRP-----PSYDGGLKVSHYVIERKDVSSPHWITVSSTCKDTAFNVQGLIENQEYIFRVMAV 7521

  Fly  2911 NKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTDFRPETSPYFPK---DF---DIERPPHDG-- 2967
            |:.|:..|.......|.|...|||.     |||       ||...:   ||   :.|:|..||
  Fly  7522 NENGMGPPLEGLNPIRAKDPIDPPS-----PPG-------SPQITEIGGDFVHLEWEKPESDGGA 7574

  Fly  2968 ----------------------------------LAQAPQFLLR-----------EQDISYGVK- 2986
                                              |.:..|:..|           |...|..||
  Fly  7575 HIQGYWIDKREVGSNTWQRVNATICAANQINCINLIEGRQYEFRIFAQNVAGLSTESSASQAVKI 7639

  Fly  2987 ----------------------DHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQA 3029
                                  :||.:....:.|.|||.:::|.....|.:|.|: ..|:.....
  Fly  7640 IDPQAASPPLIVKPLRDANCIQNHNAQFTCTINGVPKPTISWYKGAREISNGARY-HMYSEGDNH 7703

  Fly  3030 TLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHPRFLKRP---DETFIMARKNGRIEAKLV 3091
            .|.||.:...|...|...|.|:.|....|..|.|...|:....|   |..:....:|..|:....
  Fly  7704 FLNINDVFGEDADEYVCRAVNKAGAKSTRATLAIMTAPKLNVPPRFRDTAYFDKGENVVIKIPFT 7768

  Fly  3092 GIPLPEVHWFKDWKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVH 3156
            |.|.|.:||.:|.:.|.......:...:... ||.|.|....|.|.|.|:|.|..||.:..:.|.
  Fly  7769 GFPKPRIHWVRDGENIESGGHYTVEVKERHA-VLIIRDGSHLDSGPYRITAENELGSDTAIIQVQ 7832

  Fly  3157 IEENED----------------------------------------------------------- 3162
            |.:..|
  Fly  7833 ISDRPDPPRFPLIESIGTESLSLSWKAPVWDGCSDITNYYVERREHPLSSWIRVGNTRFTSMAVS 7897

  Fly  3163 ------QYIYKTYGRHPYVRS------------------------------KQLR---------- 3181
                  :|.::.:..:.|.||                              ::||
  Fly  7898 GLTPGKEYDFRIFADNVYGRSDASDTSTLIKTKESVKKKPIERKWEIDANGRKLRGKADGPVKDY 7962

  Fly  3182 ----------------------YQDKYDIGDELGRGTQGITYHAVERSSGDNYAAK-IMYGRPEL 3223
                                  ..|:|||.:|:|.|..|:.:...|||:|:.:||| |.......
  Fly  7963 DSYVFDIYSKFVPQPVEISQQSVYDRYDILEEIGTGAFGVVHRCRERSTGNIFAAKFIPVSHSVE 8027

  Fly  3224 RPFMLNELEMMNTFNHKNLIRPYDAYDTDRSVTLIMELAAGGELVRDNLLRRDY-YTERDIAHYI 3287
            :..:..|:::||..:|:.||..:||::.|..:.||:|..:||||. :.:....| .||.::.:|:
  Fly  8028 KDLIRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELF-ERITAEGYVMTEAEVINYM 8091

  Fly  3288 RQTLWGLEHMHEMGVGHMGLTIKDLLISVVGGDIIKVSDFGLSRKINRHNLSTLDYGMPEFVSPE 3352
            ||...|:.||||..:.|:.:..::::........:|:.||||:.:::.:.:..:..|..||.:||
  Fly  8092 RQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKITTGTAEFAAPE 8156

  Fly  3353 VVNKEGVNFSHDMWTVGLITYVLLGGHNPFLGIDDRETLTKIREGRWDFKDEIWTHISDDGRDFI 3417
            :||:|.|.|..|||..|:::||||.|.:||.|.:|.:||..::...|||..|.:.:||::.:|||
  Fly  8157 IVNREPVGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESFKYISEEAKDFI 8221

  Fly  3418 SRLLLYSPEERMDVKTALKHPWFFMLDRPVYDHD---YQIGTDR-------LRNYYDHFRDW--- 3469
            .:||:.:.|:||.....|.|||.      ..||.   .:|..||       ||..|:.|..:
  Fly  8222 RKLLVRNKEKRMTAHECLLHPWL------TGDHSAMKQEINRDRYLAYREKLRRKYEDFERFLLP 8280

  Fly  3470 ------YANAS---CKNY------FRRRRLSG----------CFQHPSKMVY-------PPGHVY 3502
                  |::..   .:.|      |.||:.:.          |::..|...|       .|...:
  Fly  8281 IGRLSEYSSLRKLLMEKYKIHDAVFDRRQAAPRFVIRPSSQFCYEGQSVKFYCRCIAIATPTLTW 8345

  Fly  3503 TPENTPEPLPEPRIRAKREEVVSKYLHPDY----------ELG--LIQSESHYQYGPDTYLLQL- 3554
            :..|.     |.|...|   .:.:|:..||          :.|  :|::|:||....:...|.:
  Fly  8346 SHNNI-----ELRQSVK---FMKRYVGDDYYFIINRVKLDDRGEYIIRAENHYGSREEVVFLNVQ 8402

  Fly  3555 ---------RDVNFPVRLRE-----YMKVAHRRSPSFAL---------ND--------------S 3582
                     |..:.|||.||     :.:.....:|||..         .|              :
  Fly  8403 PLPKEQPRYRTESTPVRRREPLPYTFWQEESETAPSFTFLLRPRVMQARDTCKLLCCLSGKPVPN 8467

  Fly  3583 VDWSLPVIRERRRFT---------------DIMD-------------------EEID-------- 3605
            |.|    .::.|..:               :|:|                   :|.|
  Fly  8468 VRW----YKDGRELSKYEYAMTHSDGVVTMEIIDCKPSDSGKYSCKATNCHGTDETDCVVIVEGE 8528

  Fly  3606 ----DERTRSRISMYAANESY---------------------SIRRLRTELGPRLDEYTEADAMI 3645
                ::...:...:|:.:..|                     |::......|.:::......:.|
  Fly  8529 WVTPEQAQLAHNFLYSGDRKYIEQPIKPAPLPIVTSRQYTSSSVQNTSEPQGDKVNVSNSNSSGI 8593

  Fly  3646 ETQRE---------GYP---------------------PFFREKPQTIAITENQPSHIHCFAVGD 3680
            ..:::         |.|                     |.|.:....:.|.:.:...:.|:..||
  Fly  8594 SNKKKYASNSLQAPGSPSRSRSATKELILPPDDSLMCKPEFTKPLHDLTIHDGEQLILTCYVKGD 8658

  Fly  3681 PKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVA 3745
            |:|.:.|.||...|:.|..:.:.. ::|.:.|........|.||....|.|.||....:|::.:.
  Fly  8659 PEPQISWSKNGKSLSSSDILDLRY-KNGIATLTINEVFPEDEGVITCTATNSVGAVETKCKLTIQ 8722

  Fly  3746 TLPDAPDSPEISANSGTEILLRWKQPR--DDGHSTVLCYSL---------------QYKLSNCDA 3793
            .|....:..:::|......::...:.|  .||.:..|...:               :.|.|....
  Fly  8723 PLDKNINKRKVNAGDNAPKIVSHLESRFVRDGDAVNLACRIIGAQHFDVVWLHNNKEIKPSKDFQ 8787

  Fly  3794 WTTVADNIDHEFYLLH--DLQPNTNYQFRLASKNRIGWSEMGIPVSASTVGGDAPKIHITKAMKH 3856
            :|..|:     .|.|.  ::.|.....:...:.|.||.|.....::.:..|.:..:....|....
  Fly  8788 YTNEAN-----IYRLQIAEIFPEDGGTYTCEAFNDIGESFSTCTINVTVPGDETKQPSFVKFPTS 8847

  Fly  3857 LQQLTENGHQVVPEEERVHTDYHCE--REPPN--WVTDSSVSD----KYSFISEIARGEFS 3909
            :..|...|           |.:.||  .|..|  |:.|....|    :|||..:..|..|:
  Fly  8848 VSVLEGEG-----------TTFECEIDSELLNLVWLKDGKPIDETLPRYSFTKDGHRYSFA 8897

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.